Bioreactor systems with tube supports

Patent metadata

Field	Value
Publication number	US-10150090-B2
Application number	US-201815937610-A
Country	US
Kind code	B2
Filing date	Mar 27, 2018
Priority date	Jun 16, 2010
Publication date	Dec 11, 2018
Grant date	Dec 11, 2018

Abstract

A bioreactor system includes a support housing having an interior surface bounding a compartment, the support housing having a sidewall with an opening extending therethrough and communicating with the compartment. A rack is secured to the support housing in alignment with the opening. An elongated first shaft has a first end and an opposing second end, the first end of the first shaft being secured to the rack so that the second end of the first shaft projects outwardly away from the sidewall of the support housing. A structure is secured to the first shaft towards the second end of the first shaft, the structure outwardly projecting away from the first shaft. A collapsible bag bounds a chamber and is at least partially disposed within the compartment of the support housing. A member projects from the collapsible bag and passes through the opening on the sidewall, the structure restraining movement of the member.

First claim

What is claimed is:

1. A bioreactor system comprising:
a support housing having an interior surface bounding a compartment, the support housing having a floor and a sidewall upstanding therefrom, an opening extending laterally through the sidewall and communicating with the compartment;
a rack secured to the support housing in alignment with the opening;
an elongated first shaft having a first end and an opposing second end, the first end of the first shaft being secured to the rack so that the second end of the first shaft projects outwardly away from the sidewall of the support housing;
a structure secured to the first shaft toward the second end of the first shaft, the structure outwardly projecting away from the first shaft; and
a collapsible bag bounding a chamber, the collapsible bag being at least partially disposed within the compartment of the support housing, a member projecting from the collapsible bag and passing through the opening on the sidewall, the structure restraining movement of the member.

2. The bioreactor system as recited in claim 1 , wherein the structure has a bend.

3. The bioreactor system as recited in claim 2 , wherein the structure at least partially encircles the member.

4. The bioreactor system as recited in claim 1 , wherein the structure is resiliently flexible.

5. The bioreactor system as recited in claim 1 , wherein the rack is at least partially disposed within the opening of the sidewall.

6. The bioreactor system as recited in claim 5 , wherein the rack at least partially spans across the opening.

7. The bioreactor system as recited in claim 1 , wherein the rack comprises a flat plate.

8. The bioreactor system as recited in claim 1 , wherein the sidewall comprises a movable door, the door at least partially bounding the opening.

9. The bioreactor system as recited in claim 1 , wherein the member comprises a tube.

10. The bioreactor system as recited in claim 1 , further comprising a rotatable impeller disposed within the chamber of the collapsible bag.

11. The bioreactor system as recited in claim 1 , further comprising an elongated second shaft having a first end and an opposing second end, the first end of the second shaft being secured to the rack so that the second end of the second shaft projects outwardly away from the sidewall of the support housing.

12. The bioreactor system as recited in claim 1 , wherein the rack is disposed entirely outside of the compartment of the support housing.

13. A bioreactor system comprising:
a support housing having an interior surface bounding a compartment, the support housing having a floor and a sidewall upstanding therefrom, an opening extending laterally through the sidewall and communicating with the compartment;
a rack secured to the support housing in alignment with the opening;
an elongated first shaft having a first end and an opposing second end, the first end of the first shaft being secured to the rack so that the second end of the first shaft projects outwardly away from the sidewall of the support housing;
a structure secured to the first shaft toward the second end of the first shaft, the structure outwardly projecting away from the first shaft; and
a collapsible bag bounding a chamber, the collapsible bag being at least partially disposed within the compartment of the support housing, a member projecting from the collapsible bag and passing through the opening on the sidewall, the member being supported by the structure mounted to the second end of the first shaft.

14. The bioreactor system as recited in claim 13 , wherein the structure has a curve.

15. The bioreactor system as recited in claim 13 , wherein the rack is at least partially disposed within the opening of the sidewall.

16. The bioreactor system as recited in claim 15 , wherein the rack at least partially spans across the opening.

17. The bioreactor system as recited in claim 13 , wherein the rack comprises a flat plate.

18. The bioreactor system as recited in claim 13 , wherein the sidewall comprises a movable door, the door at least partially bounding the opening.

19. The bioreactor system as recited in claim 13 , wherein the member comprises a tube.

20. The bioreactor system as recited in claim 13 , further comprising a rotatable impeller disposed within the chamber of the collapsible bag.

21. The bioreactor system as recited in claim 13 , further comprising an elongated second shaft having a first end and an opposing second end, the first end of the second shaft being secured to the rack so that the second end of the second shaft projects outwardly away from the sidewall of the support housing.

Assignees

• Life Technologies Corp

Inventors

• Goodwin Michael E
• Cornia Wade A
• Lee Jacob D

Classifications

• B01F7/00341

  Operations & Transport · mapped topic

• B01F13/003

  Operations & Transport · mapped topic

• B01F15/0085

  Operations & Transport · mapped topic

• B01F7/00691

  Operations & Transport · mapped topic

• B01F7/1695 Primary

  Operations & Transport · mapped topic