Vaccines and diagnostics for the ehrlichioses
US-10131705-B2 · Nov 20, 2018 · US
Immunoreactive protein orthologs of Ehrlichia canis and E. chaffeensis
USRE46254E · US · E1
| Field | Value |
|---|---|
| Publication number | US-RE46254-E |
| Application number | US-200614855023-A |
| Country | US |
| Kind code | E1 |
| Filing date | Jun 15, 2006 |
| Priority date | Jun 16, 2005 |
| Publication date | Dec 27, 2016 |
| Grant date | Dec 27, 2016 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
The present invention concerns gp36 immunoreactive compositions for E. canis and gp 47 immunoreactive compositions for E. chaffeensis. In particular, epitopes for E. canis gp36 and E. chaffeensis gp 47 are disclosed. In certain embodiments, the immunoreactive compositions comprise tandem repeats having carbohydrate moieties.
First claim
Opening claim text (preview).
What is claimed is: 1. A composition comprising one or more isolated polypeptides, said polypeptides having a sequence comprising (a) SEQ ID NO:22, SEQ ID NO:45 or SEQ ID NO:46; (b) SEQ ID NO:23 or SEQ ID NO:24; or (c) a sequence that is at least 90% identical to one or more sequences in (a) or (b), wherein the polypeptide is one or more isolated polypeptides are 100 amino acid residues or less in length, wherein said one or more polypeptides are bound to a solid matrix or to an immobilizing surface. 2. The composition of claim 1 , wherein the polypeptide is one or more polypeptides are chemically synthesized. 3. The composition of claim 1 , further comprising a pharmaceutically acceptable excipient. 4. The composition of claim 1 , wherein one or more of the polypeptide comprises polypeptides comprise two or more carbohydrate moieties. 5. The composition of claim 1 , comprising wherein the one or more isolated polypeptides having have a sequence comprising (a) SEQ ID NO:22, SEQ ID NO:45 or SEQ ID NO:46; or (b) SEQ ID NO:23 or SEQ ID NO:24. 6. The composition of claim 5 , wherein the polypeptide at least one of the polypeptides comprises SEQ ID NO:22. 7. The composition of claim 5 , wherein the polypeptide at least one of the polypeptides comprises SEQ ID NO:45. 8. The composition of claim 5 , wherein the polypeptide at least one of the polypeptides comprises SEQ ID NO:46. 9. The composition of claim 5 , wherein the polypeptide at least one of the polypeptides comprises SEQ ID NO:23. 10. The composition of claim 5 , wherein the polypeptide at least one of the polypeptides comprises SEQ ID NO:24. 11. The composition of claim 1, wherein the solid matrix is an immunoblot. 12. The composition of claim 11, wherein the immunoblot is a nitrocellulose membrane. 13. The composition of claim 1, wherein one or more of the polypeptides are bound to a ELISA plate. 14. The composition of claim 1, wherein one or more of the polypeptides are bound to a dot blot. 15. The composition of claim 1, wherein one or more of the polypeptides are bound to a western blot. 16. The composition of claim 1, wherein one or more of the polypeptides are bound to an immobilizing surface, further defined as the surface of an ELISA plate.
Assignees
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Classifications
from Richettsiales (O) · CPC title
- C07K16/1246Primary
Rickettsiales (O) · CPC title
from Richettsiales (o) · CPC title
from bacteria · CPC title
Detection of antigens from microorganism in sample from host · CPC title
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Frequently asked questions
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- What does patent USRE46254E cover?
- The present invention concerns gp36 immunoreactive compositions for E. canis and gp 47 immunoreactive compositions for E. chaffeensis. In particular, epitopes for E. canis gp36 and E. chaffeensis gp 47 are disclosed. In certain embodiments, the immunoreactive compositions comprise tandem repeats having carbohydrate moieties.
- Who is the assignee on this patent?
- Res Dev Foundation
- What technology area does this patent fall under?
- Primary CPC classification C07K16/1246. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Dec 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (E1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).