Nanochannel arrays and their preparation and use for high throughput macromolecular analysis
US-2017343509-A1 · Nov 30, 2017 · US
US9522820B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9522820-B2 |
| Application number | US-74259808-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 12, 2008 |
| Priority date | Nov 13, 2007 |
| Publication date | Dec 20, 2016 |
| Grant date | Dec 20, 2016 |
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A method is provided to prepare one or more microfluidic channels on a receptive material by applying an image-forming material to a heat sensitive thermoplastic receptive material in a designed pattern and heating the material under conditions that reduce the size of the thermoplastic receptive material by at least about 60%. In an alternative aspect, the microfluidic channels on receptive material are prepared by etching a designed pattern into a heat sensitive thermoplastic material support and then heating the material under conditions that reduce the size of the thermoplastic receptive material by at least about 60%.
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What is claimed is: 1. A method to prepare a textured metal surface, comprising the steps of: a) depositing a metal film onto a heat sensitive thermoplastic receptive material; and b) reducing the heat sensitive thermoplastic receptive material with the metal film deposited thereon in plane with respect to at least one of width and length, by at least about 60%, wherein the metal film deposited on the heat sensitive thermoplastic receptive material forms wrinkles having a height or thickness, wherein a height or thickness of the wrinkles is over 500% the thickness of the metal film deposited on the heat sensitive thermoplastic receptive material prior to reducing in plane with respect to at least one of width and length; thereby preparing a textured metal surface. 2. The method of claim 1 , wherein the heat sensitive thermoplastic receptive material is uni-axially biased prior to performing steps a) and b). 3. The method of claim 1 , wherein the metal film is deposited by sputter coating, evaporation or chemical vapor deposition. 4. The method of claim 1 , wherein the metal film is deposited in a thickness from about 2 nanometers to about 100 nanometers. 5. The method of claim 1 , wherein the metal film comprises one or more of the group of silver, gold or copper. 6. The method of claim 1 , wherein the heat sensitive thermoplastic receptive material is reduced to achieve a surface texture in the range of from about 100 nanometers to about 5 micrometers. 7. The method of claim 1 , wherein the heat sensitive thermoplastic receptive material is polystyrene. 8. The method of claim 1 , wherein the metal film is deposited in a desired pattern. 9. The method of claim 1 , wherein the heat sensitive thermoplastic receptive material is reduced by heating.
using thermal evaporation (formation of epitaxial layers by a deposition process H10P14/6349) · CPC title
using decomposition or reaction of gaseous or vapour phase compounds, i.e. chemical vapour deposition (deposition by physical ablation of a target H10P14/6329) · CPC title
Operations & Transport · mapped topic
Electricity · mapped topic
Microfluidics not provided for in B81B2201/051 - B81B2201/054 · CPC title
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