Conjugated polymeric material and uses thereof
US-9827323-B2 · Nov 28, 2017 · US
Curcumin coated magnetite nanoparticles for biomedical applications
US9468691B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9468691-B2 |
| Application number | US-201314372698-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 17, 2013 |
| Priority date | Jan 17, 2012 |
| Publication date | Oct 18, 2016 |
| Grant date | Oct 18, 2016 |
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- Title
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Abstract
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The present invention discloses biocompatible, stable curcumin or its derivatives coated ultra-small super paramagnetic iron oxide nanoparticles (USPION) for biomedical applications. Disclosed herein is also a simple one-pot process for the synthesis of biocompatible, stable curcumin or its derivatives coated ultra-small superparamagnetic iron oxide nanoparticles in absence of a linker or binder. The curcumin or its derivatives coated ultra-small super paramagnetic iron oxide nanoparticles of the present invention retains the medicinal, radical scavenging and fluorescence properties of curcumin.
First claim
Opening claim text (preview).
We claim: 1. Curcumin coated magnetite nanoparticles comprising biocompatible, stable curcumin coated ultra-small super paramagnetic iron oxide nanoparticles devoid of any linker or binder, the curcumin coated magnetite nanoparticles having a particle size of about 3 nm, wherein the curcumin coated magnetite nanoparticle retains medicinal, radical scavenging and fluorescence properties of curcumin, for biomedical applications, wherein curcumin is directly coated on ultra-small super paramagnetic iron oxide nanoparticles. 2. A method for magnetic resonance or fluorescent imaging, the method comprising administering curcumin coated magnetite nanoparticles of claim 1 to a subject, and performing an imaging step. 3. A method for delivering curcumin to a subject in need thereof comprising administering curcumin coated magnetite nanoparticles, of claim 1 . 4. The curcumin coated magnetite nanoparticles of claim 1 , which are biocompatible, stable curcumin coated ultra-small iron oxide nanoparticles devoid of any linker or binder for use as a contrast agent for magnetic resonance fluorescent imaging. 5. The curcumin coated magnetite nanoparticles of claim 1 , which are biocompatible, stable, curcumin coated ultra-small iron oxide nanoparticles devoid of any linker or binder for use in delivering curcumin to a subject in need thereof.
Assignees
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Classifications
Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery · CPC title
having a drug-free core with discrete complete coating layer containing drug (adsorbates of liquid drug formulations on inert powders without simultaneous granulation step A61K9/141; with further drug-free outer coating A61K9/5078; drug conjugated to non-active particles A61K47/6921) · CPC title
- A61K49/1833Primary
having a (super)(para)magnetic core coated or functionalised with a small organic molecule (oligomeric, polymeric, dendrimeric A61K49/1851) · CPC title
Processes · CPC title
Small organic molecules (oligomers, polymers, dendrimers A61K49/0054) · CPC title
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- What does patent US9468691B2 cover?
- The present invention discloses biocompatible, stable curcumin or its derivatives coated ultra-small super paramagnetic iron oxide nanoparticles (USPION) for biomedical applications. Disclosed herein is also a simple one-pot process for the synthesis of biocompatible, stable curcumin or its derivatives coated ultra-small superparamagnetic iron oxide nanoparticles in absence of a linker or binde…
- Who is the assignee on this patent?
- Council Scient Ind Res
- What technology area does this patent fall under?
- Primary CPC classification A61K49/1833. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Oct 18 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).