Nanoparticles and methods of making

US2017143854A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2017143854-A1
Application numberUS-201615359606-A
CountryUS
Kind codeA1
Filing dateNov 22, 2016
Priority dateNov 23, 2015
Publication dateMay 25, 2017
Grant date

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Abstract

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Magnetic nanoparticles and synthesis of synthesis are described.

First claim

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What is claimed is: 1 . A method of preparing a redox-active nanoparticle comprising: selecting a solvent to optimize redox tuning of a reaction medium; decomposing a precursor compound at a reflux temperature of the solvent to produce the nanoparticle. 2 . The method of claim 1 , further comprising oxidizing the nanoparticle. 3 . The method of claim 2 , wherein the oxidized nanoparticle is an inverse spinel phase iron oxide. 4 . The method of claim 1 , wherein the oxidized nanoparticle includes iron, manganese, cobalt, nickel, copper, or zinc or binary or ternary mixtures thereof. 5 . The method of claim 1 , wherein the solvent includes dibenzyl ether, diphenyl ether, anisole, phenetole, an aromatic ester, an aromatic acetal, an aromatic aminal or an aromatic anhydride. 6 . The method of claim 1 , wherein the solvent is a mixture. 7 . The method of claim 6 , wherein the mixture includes a high boiling point alkene and a high boiling point ether. 8 . The method of claim 7 , wherein the high boiling point is at least 280° C. 9 . The method of claim 7 , wherein the solvent includes a mixture of two or more of octadecane, 1-octadecene (ODE), squalene (SQE), dioctyl ether, and dibenzyl ether (DBE). 10 . The method of claim 1 , wherein the compound includes an iron oleate. 11 . The method of claim 1 , wherein the nanoparticle includes ferrite. 12 . The method of claim 1 , wherein the nanoparticle has a size of between 7 and 30 nm. 13 . A magnetic nanoparticle population comprising a plurality monodisperse ferrite particles having a size of between 7 and 30 nm. 14 . A method of imaging comprising introducing the nanoparticle population of claim 13 into a subject; and creating a magnetic particle imaging signal of the subject.

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What does patent US2017143854A1 cover?
Magnetic nanoparticles and synthesis of synthesis are described.
Who is the assignee on this patent?
Massachusetts Inst Technology
What technology area does this patent fall under?
Primary CPC classification A61K49/1818. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Thu May 25 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).