Curable composition for dentistry

Patent metadata

Field	Value
Publication number	US-2023039514-A1
Application number	US-202017788253-A
Country	US
Kind code	A1
Filing date	Nov 26, 2020
Priority date	Dec 24, 2019
Publication date	Feb 9, 2023
Grant date	—

Abstract

Provided is a curable composition that is for dentistry and that contains: a polymerizable monomer (A); an inorganic filler (B) having an average particle size of 0.1-1 μm; an organic-inorganic composite filler (C) having an aggregate structure in which inorganic primary particles having an average particle size of 10-1000 nm are bonded together through a resin layer covering the surface of the particles, to form a void having a specific pore volume; and a polymerization initiator (D). In the organic-inorganic composite filler (C), a curved surface-shaped organic-inorganic composite filler (C1) formed of organic-inorganic composite aggregate particles having a curved surface shape, and an amorphous organic-inorganic composite filler (C2) formed of amorphous organic-inorganic composite aggregate particles having an edge portion, are mixed such that C1/(C1+C2) equals 0.2-0.8 in terms of the number of particles having a particle size of 5 μm or more.

First claim

1 . A curable composition for dentistry, comprising
a polymerizable monomer (A); an inorganic filler (B) having an average particle size of 0.1 to 1 μm; an organic-inorganic composite filler (C), and a polymerization initiator (D), the organic-inorganic composite filler (C) comprising organic-inorganic composite aggregate particles having an aggregated structure where inorganic primary particles having an average particle size of 10 to 1,000 nm are bonded together through a resin layer covering at least part of the surface of the inorganic primary particles so as to form a void; the organic-inorganic composite filler (C) having pores where a total pore volume of pores having a pore size measured by a nitrogen adsorption method in the range of 1 to 500 nm is 0.01 to 0.30 cm 3 /g; the organic-inorganic composite filler (C) having an average particle size of 10 to 100 μm; wherein the organic-inorganic composite filler (C) comprises a curved surface-shaped organic-inorganic composite filler (C1) composed of organic-inorganic composite aggregate particles having a curved surface shape, and an irregular-shaped organic-inorganic composite filler (C2) composed of organic-inorganic composite aggregate particles having an irregular shape which comprises an edge portion, and wherein a content ratio {C1/(C1+C2)} of the curved surface-shaped organic-inorganic composite filler (C1) accounting for the entire organic-inorganic composite filler (C) is 0.2 to 0.8, the content ratio being expressed in terms of a ratio of the total number of the curved surface-shaped organic-inorganic composite aggregate particles which have a particle size of 5 μm or more and which constitute the curved surface-shaped organic-inorganic composite filler (C1), accounting for the total number of the organic-inorganic composite aggregate particles having a particle size of 5 μm or more.

2 . The curable composition for dentistry according to claim 1 , wherein the organic-inorganic composite filler (C) is an organic-inorganic composite filler obtained by spray-drying inorganic primary particles to form aggregate particles, and impregnating pores of the aggregate particles with a polymerizable monomer component, followed by polymerization.

3 . The curable composition for dentistry according to claim 1 , wherein the amorphous organic-inorganic composite filler (C2) is composed of a pulverized product of the curved surface-shaped organic-inorganic composite filler (C1).

4 . The curable composition for dentistry according to claim 1 , wherein the contents of the inorganic filler (B) and the organic-inorganic composite filler (C) are 100 to 300 parts by mass based on 100 parts by mass of the polymerizable monomer (A), respectively, and the total content of the inorganic filler (B) and the organic-inorganic composite filler (C) is 250 to 550 parts by mass based on 100 parts by mass of the polymerizable monomer (A).

5 . The curable composition for dentistry according to claim 1 , wherein both the shape of the inorganic particles constituting the inorganic filler (B) and the shape of the inorganic primary particles in the organic-inorganic composite aggregate particles constituting the organic-inorganic composite filler (C) are spherical or substantially spherical.

Assignees

• Tokuyama Dental Corp

Inventors

• Morisaki Hiroshi
• Yamazaki Tatsuya
• Matsuo Takuma
• Akizumi Hironobu

Classifications

• A61K6/849 Primary

  comprising inorganic cements · CPC title

• A61K6/62

  Photochemical radical initiators · CPC title

• A61K6/17 Primary

  Particle size · CPC title

• A61K6/76

  comprising silicon-containing compounds · CPC title

• A61K6/878

  Zirconium oxide · CPC title