Methods of treatment of the dental pulp and filling root canals using water-based material

Patent metadata

Field	Value
Publication number	US-9801792-B2
Application number	US-201414149340-A
Country	US
Kind code	B2
Filing date	Jan 7, 2014
Priority date	Feb 9, 2007
Publication date	Oct 31, 2017
Grant date	Oct 31, 2017

Abstract

A dental composition comprising: a) about 1 to about 80% by weight of particulate material including: (i) calcium silicate, calcium aluminate, tetracalcium aluminoferrite, calcium phosphate, calcium sulfate, silica, alumina, calcium oxide, calcium hydroxide, or mixtures thereof; and b) about 1 to about 50% by weight liquid carrier including: (i) water-soluble polymer, (ii) surfactant, the surfactant is selected from the group consisting of alkyl sulfates, alkyl ether sulfates, and sarcosinates, and mixtures thereof; and (iii) water; wherein the particulate and liquid carrier being mixed together to form a hydrate gel material that can harden.

First claim

What is claimed is:

1. A method of treating a root canal in a tooth, comprising the steps of:
a) preparing the root canal in the tooth to be treated,
b) providing a composition comprising:
(i) a mixture of about 1% to about 80% by weight of particulate material including calcium silicate, calcium aluminate, tetracalcium aluminoferrite, calcium phosphate, calcium sulfate, silica, alumina, calcium oxide, calcium hydroxide and mixtures thereof; and
(ii) about 1% to about 80% by weight of a liquid carrier including:
(1) water-soluble polymer;
(2) surfactant, the surfactant is selected from the group consisting of alkyl sulfates, alkyl ether sulfates, sarcosinates, and mixtures thereof; and
(3) water; and
wherein the ratio of the surfactant to the water-soluble polymer being no greater than 6 to 1; and
wherein the mixture, the liquid carrier, or both further include a humectant, a hydroxyapatite, or both a humectant and a hydroxyapatite;

c) introducing the composition into the tooth from coronal or apical openings and allowing the composition to harden.

2. The method of claim 1 , wherein the water-soluble polymer is selected from the group consisting of polyvinyl alcohols, polyvinyl-pyrrolidone (PVP), partially hydrolyzed polyvinyl acetates, (PVAc), polyacrylic acid (PAA), polymethacrylic acid (PMA), hyaluronic acid, water-soluble poly-saccharides, poly amino-acids, and mixtures thereof.

3. The method of claim 1 , wherein the hydroxyapatite is present in an amount of about 1 to about 30% by weight.

4. The method of claim 1 , wherein the sealing composition further comprises about 1 to about 40% by weight of a radiopaque component.

5. The method of claim 4 , wherein the radiopaque component is selected from the group consisting of bismuth oxide, barium sulfate, tantalum oxide, cerium oxide, tin oxide, zirconium oxide compounds, radiopaque glasses containing tantalum, barium and strontium, and mixtures thereof.

6. The method of claim 1 , wherein the particulate material comprises a mixture of tricalcium silicate and dicalcium silicate particles.

7. The method of claim 1 , wherein the particulate material comprises about 20 to about 80 wt. % tricalcium silicate; about 20 to about 50 wt. % dicalcium silicate; about 1 to about 20 wt. % tricalcium aluminate, about 1 to about 20 wt. % tetracalcium aluminoferrite; about 1 to about 15 wt. % calcium sulfate dihydrate, and about 1 to about 50 wt. % radiopaque component.

8. The method of claim 1 , wherein the method comprises using the composition to seal at least a portion of the tooth.

9. The method of claim 1 , wherein the method comprises using the composition to repair root perforations.

10. The method of claim 1 , wherein the method comprises using the composition to repair root resorption.

11. The method of claim 1 , wherein the method comprises using the composition to fill root ends.

12. The method of claim 1 , wherein the method comprises using the composition to cap at least a portion of the pulp that has been exposed.

13. The method of claim 1 , wherein the method comprises using the composition to line a cavity preparation where a pulp-exposure is possible.

14. The method of claim 1 , wherein the method comprises using the composition to obturate root canals.

15. The method of claim 1 , wherein the method comprises using the composition to cover a root access opening in a root after a pulpotomy has been performed.

16. The method of claim 1 , wherein the method comprises using the composition to seal a root canal after gutta-percha has been introduced into the canal.

17. The method of claim 1 , wherein the composition further comprises anti-bacterial and/or anti-microbial agents.

18. The method of claim 17 , wherein the anti-microbial agent includes chlorhexidine gluconate.

19. The method of claim 7 , wherein the particulate has an average particle size in the range of about 1 μm to about 40 μm.

20. The method of claim 7 , wherein the particulate material has an average particle size in the range of about 1 μm to about 15 μm.

Assignees

• Dentsply Int Inc

Inventors

• Primus Carolyn M
• Gutmann James L
• Breuer Miklos M
• Jefferies Steven R

Classifications

• A61P31/04

  Antibacterial agents · CPC title

• A61P31/00

  Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics · CPC title

• A61P1/02

  Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis · CPC title

• A61K6/71

  Fillers · CPC title

• A61K6/70

  comprising inorganic additives · CPC title