Temporary root canal sealer dispersion

Patent metadata

Field	Value
Publication number	US-9895294-B2
Application number	US-201013257147-A
Country	US
Kind code	B2
Filing date	Mar 18, 2010
Priority date	Mar 18, 2009
Publication date	Feb 20, 2018
Grant date	Feb 20, 2018

Abstract

A temporary root canal sealer dispersion having a pH of at least 9 and comprising: (i) an aqueous dispersion medium comprising an oligomer and/or polymer having Lewis basic groups, and optionally a hydroxide of an alkali metal and/or a hydroxide of an alkaline earth metal, and (ii) a dispersed phase comprising a radio-opaque filler, wherein the weight ratio of oligomer and/or polymer having Lewis basic groups to hydroxide of an alkali metal and/or hydroxide of an alkaline earth metal is at least 0.5 when said aqueous dispersion medium comprises a hydroxide of an alkali metal and/or a hydroxide of an alkaline earth metal.

First claim

What is claimed is:

1. A temporary root canal sealer dispersion comprising:
(i) an aqueous dispersion medium comprising an oligomer and/or polymer having Lewis basic groups, where the oligomer and/or polymer is a polyamine, and optionally a hydroxide of an alkali metal and/or a hydroxide of an alkaline earth metal, and
(ii) a dispersed phase comprising a radio-opaque filler, wherein the weight ratio of oligomer and/or polymer having Lewis basic groups to hydroxide of an alkali metal and/or hydroxide of an alkaline earth metal is at least 0.5 when said aqueous dispersion medium comprises a hydroxide of an alkali metal and/or a hydroxide of an alkaline earth metal,
wherein the temporary root canal sealer dispersion has a pH of at least 9,
wherein oligomer has a weight average molecular weight, Mw, of between 500 and 10,000 Da and the polymer has a weight average molecular weight, Mw, of between 10,000 and 200,000 Da,
wherein the oligomer and/or polymer is present in an amount of from 25 to 60 weight percent based on the total amount of the composition,
wherein the radio-opaque filler is present in an amount of from 10 to 60 weight percent based on the total amount of the composition, and
wherein water is present in an amount of from 20 to 80 weight percent based on the total amount of the composition.

2. The temporary root canal sealer dispersion of claim 1 , wherein the weight ratio of oligomer and/or polymer and hydroxide of an alkali metal and/or hydroxide of an alkaline earth metal to radio-opaque filler is between 0.1 and 10.

3. The temporary root canal sealer dispersion of any of claim 1 , wherein the weight ratio of radio-opaque filler to oligomer and/or polymer is at least 0.75.

4. The temporary root canal sealer dispersion of claim 1 , wherein the hydroxide of an alkali metal and/or hydroxide of an alkaline earth metal is selected from any of the hydroxides of sodium, potassium, caesium, calcium, strontium and barium, either singly or in combination, or wherein the hydroxide of an alkali metal and/or hydroxide of an alkaline earth metal is derived in situ from a precursor selected from any of the oxides of sodium, potassium, caesium, calcium, strontium and barium, either singly or in combination.

5. The temporary root canal sealer dispersion of claim 1 , wherein the hydroxide of an alkali metal and/or hydroxide of an alkaline earth metal is present in an amount of from 1 to 40 weight percent based on the total amount of the composition.

6. The temporary root canal sealer dispersion of claim 1 , wherein the radio-opaque filler is selected from any of bismuth trioxide, bismuth carbonate, bismuth oxy-chloride, bismuth subnitrate, zirconium oxide, barium sulfate, barium tungstate and calcium tungstate, either singly or in combination.

7. The temporary root canal sealer dispersion of claim 1 , which has a radio-opacity of greater than 2.5 mm/mm aluminum.

8. The temporary root canal sealer dispersion of claim 1 , wherein the aqueous dispersion medium additionally contains an antiseptic.

9. The temporary root canal sealer dispersion of claim 1 , wherein the aqueous dispersion medium additionally contains a pH-indicator.

10. The temporary root canal sealer dispersion of any of the preceding claims, wherein the aqueous dispersion medium additionally contains a humectant.

11. A kit-of-parts for the formation of the temporary root canal sealer dispersion according to claim 1 , wherein the oligomer and/or polymer of the aqueous dispersion medium is packaged separately from the radio-opaque filler and, if comprised in said kit-of-parts, the hydroxide of an alkali metal and/or hydroxide of an alkaline earth metal and/or precursor or precursors thereof.

12. The temporary root canal sealer dispersion of claim 8 , wherein the antiseptic is chlorhexidine.

13. The temporary root canal sealer dispersion of claim 9 , wherein the pH-indicator is thymol blue.

14. The temporary root canal sealer dispersion of claim 10 , wherein the humectant is sorbitol.

Assignees

• Klee Joachim E
• Weber Christoph
• Gruetzner Andreas E
• Dentsply Sirona Inc

Inventors

• Klee Joachim E
• Weber Christoph
• Gruetzner Andreas E

Classifications

• A61K6/849

  comprising inorganic cements · CPC title

• A61K6/54 Primary

  Filling; Sealing · CPC title

• A61K6/878 Primary

  Zirconium oxide · CPC title

• A61K6/0681

  Human Necessities · mapped topic

• A61K6/0038 Primary

  Human Necessities · mapped topic