Sprayable tissue adhesive with biodegradation for wound treatment

US12564656B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12564656-B2
Application numberUS-202318192946-A
CountryUS
Kind codeB2
Filing dateMar 30, 2023
Priority dateMar 30, 2022
Publication dateMar 3, 2026
Grant dateMar 3, 2026

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Provided are compositions and methods that involve viscoelastic poly(lactide-co-caprolactone) (PLCL) mixtures for use in wound healing. The PLCL mixtures provide an improved anti-fibrotic yet tissue-adhesive polymer sealant. The PLCL mixtures can be applied to a variety of wounds arising from surgical and non-surgical tissue damage.

First claim

Opening claim text (preview).

What is claimed is: 1 . A composition consisting essentially of a mixture of 40 k and 5 k poly(L-lactide-co-caprolactone) (PLCL), wherein the 40 k and 5 k PLCL are present in a 70:30 mass ratio, respectively, wherein the composition is free of poly(lactic-co-glycolic acid) (PLGA), poly(ethylene glycol) (PEG) and nanoparticles, and when in contact with a tissue wound the composition is optionally a solid adhesive.

Assignees

Inventors

Classifications

  • obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds · CPC title

  • Sprayable compositions · CPC title

  • Flowable or injectable implant compositions · CPC title

  • obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds (A61L24/043 takes precedence) · CPC title

  • Materials resorbable by the body · CPC title

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Frequently asked questions

Answers are generated from the same data shown on this page.

What does patent US12564656B2 cover?
Provided are compositions and methods that involve viscoelastic poly(lactide-co-caprolactone) (PLCL) mixtures for use in wound healing. The PLCL mixtures provide an improved anti-fibrotic yet tissue-adhesive polymer sealant. The PLCL mixtures can be applied to a variety of wounds arising from surgical and non-surgical tissue damage.
Who is the assignee on this patent?
Univ Maryland, Childrens Nat Medical Ct
What technology area does this patent fall under?
Primary CPC classification A61L24/0026. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Mar 03 2026 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).