Surface stabilization of biosensors

Patent metadata

Field	Value
Publication number	US-12139758-B2
Application number	US-202418407234-A
Country	US
Kind code	B2
Filing date	Jan 8, 2024
Priority date	Mar 5, 2015
Publication date	Nov 12, 2024
Grant date	Nov 12, 2024

Abstract

A sensor apparatus includes a substrate, a semiconductor device disposed over the substrate, the semiconductor device having a surface electrode structure, and a saccharide coating formed over the surface electrode structure. The saccharide coating can be removed prior to use. The semiconductor device can further include a well and optionally a bead disposed in the well.

First claim

What is claimed:

1. A treatment system comprising:
a plurality of reagent vessels;
a manifold in fluidic communication with the plurality of reagent vessels; and
a treatment apparatus including a slidable deck to receive sensor apparatuses, a clamp having resilient apparatus guides, and an access manifold in fluidic communication with the manifold and including ports to fluidically connect with flow cells of the sensor apparatuses, when the slidable deck is positioned under the clamp, the clamp movable to motivate the slidable deck downward to engage the access manifold.

Assignees

• Life Technologies Corp

Inventors

• Waggoner Philip
• Ball James A
• Minto Michael L
• Cox David M
• Hinz Wolfgang
• Mastroianni Alexander
• Gray Jeremy
• Glazer Marc
• Parker Scott
• GORRELL Kimberly

Classifications

• G01N27/4145 Primary

  specially adapted for biomolecules, e.g. gate electrode with immobilised receptors · CPC title

• C12Q2565/607

  being a sensor, e.g. electrode · CPC title

• C12Q2527/125

  Specific component of sample, medium or buffer · CPC title

• C12Q2527/119

  pH · CPC title

• C12Q1/6869 Primary

  Methods for sequencing · CPC title