Immunoreactive protein orthologs of Ehrlichia canis and E. chaffeensis

US11459379B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11459379-B2
Application numberUS-202016809105-A
CountryUS
Kind codeB2
Filing dateMar 4, 2020
Priority dateJun 16, 2005
Publication dateOct 4, 2022
Grant dateOct 4, 2022

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  2. Abstract

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Abstract

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The present invention concerns gp36 immunoreactive compositions for E. canis and gp 47 immunoreactive compositions for E. chaffeensis. In particular, epitopes for E. canis gp36 and E. chaffeensis gp 47 are disclosed. In certain embodiments, the immunoreactive compositions comprise tandem repeats having carbohydrate moieties.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of inducing an immune response in a mammalian subject, comprising administering to the subject a pharmaceutical composition comprising a therapeutically effective amount of a glycosylated recombinant polypeptide comprising SEQ ID NO:22 or SEQ ID NO:23 and a pharmaceutically acceptable excipient. 2. The method of claim 1 , wherein the recombinant polypeptide is less than 250 amino acids in length. 3. The method of claim 1 , wherein the recombinant polypeptide is less than 220 amino acids in length. 4. The method of claim 1 , wherein the recombinant polypeptide is less than 200 amino acids in length. 5. The method of claim 1 , wherein the recombinant polypeptide is less than 150 amino acids in length. 6. The method of claim 1 , wherein the subject is a human. 7. A method of inducing an immune response in a mammalian subject, comprising administering to the subject a pharmaceutical composition comprising a therapeutically effective amount of a glycosylated recombinant polypeptide comprising SEQ ID NO:45 or SEQ ID NO:46 and a pharmaceutically acceptable excipient. 8. The method of claim 7 , wherein the recombinant polypeptide is less than 250 amino acids in length. 9. The method of claim 7 , wherein the recombinant polypeptide is less than 220 amino acids in length. 10. The method of claim 7 , wherein the recombinant polypeptide is less than 200 amino acids in length. 11. The method of claim 7 , wherein the recombinant polypeptide is less than 150 amino acids in length. 12. The method of claim 7 , wherein the subject is a human.

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What does patent US11459379B2 cover?
The present invention concerns gp36 immunoreactive compositions for E. canis and gp 47 immunoreactive compositions for E. chaffeensis. In particular, epitopes for E. canis gp36 and E. chaffeensis gp 47 are disclosed. In certain embodiments, the immunoreactive compositions comprise tandem repeats having carbohydrate moieties.
Who is the assignee on this patent?
Res Found Dev
What technology area does this patent fall under?
Primary CPC classification C07K16/1246. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Oct 04 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).