Luminescent material

Patent metadata

Field	Value
Publication number	US-11034887-B2
Application number	US-202016852722-A
Country	US
Kind code	B2
Filing date	Apr 20, 2020
Priority date	May 9, 2016
Publication date	Jun 15, 2021
Grant date	Jun 15, 2021

Abstract

The invention relates to a material represented by the following formula (I)(M′)8(M″M′″)6O24(X,X′)2:M″″   formula (I).Further, the invention relates to a luminescent material, and to different medical imaging and diagnostic methods of using the material. Also disclosed is a method of securely identifying an item using the material.

First claim

What is claimed is:

1. A method of medical imaging a body fluid or tissue of a human or animal, the method comprising:
introducing a material into a body fluid or tissue of a human or animal, wherein the material is represented by the following formula (I)
(M′) 8 (M″M′″) 6 O 24 (X,X′) 2 :M″″   formula (I)

wherein
M′ represents a monoatomic cation of an alkali metal selected from Group 1 of the IUPAC periodic table of the elements, or any combination of such cations;
M″ represents a trivalent monoatomic cation of an element selected from Group 13 of the IUPAC periodic table of the elements, or of a transition element selected from any of Groups 3-12 of the IUPAC periodic table of the elements, or any combi-nation of such cations;
M′″ represents a monoatomic cation of an element selected from Group 14 of the IUPAC periodic table of the elements, or of an element selected from any of Groups 13 and 15 of the IUPAC periodic table of the elements, or of Zn, or any combination of such cations;
X represents an anion of an element selected from Group 17 of the IUPAC periodic table of the elements, or any combination of such anions, or wherein X is absent;
X′ represents an anion of an element selected from Group 16 of the IUPAC periodic table of the elements, or any combination of such anions, or wherein X′ is absent; and
M″″ represents a dopant cation of an element selected from transition metals of the IUPAC periodic table of the elements, or any combination of such cations;

with the proviso that at least one of X and X′ is present; and
exposing the material to light of a first wavelength causing it to emit at least part of the received energy as light at a second wavelength which is longer than the first wavelength.

2. The method of claim 1 , wherein M′ represents a monoatomic cation of an alkali metal selected from Group 1 of the IUPAC periodic table of the elements, or any combination of such cations, with the proviso that M′ does not represent the monoatomic cation of Na alone.

3. The method of claim 1 , wherein M′ represents a combination of at least two monoatomic cations of different alkali metals selected from Group 1 of the IUPAC periodic table of the elements.

4. The method of claim 1 , wherein M′ represents a combination of at least two monoatomic cations of different alkali metals selected from a group consisting of Li, Na, K, and Rb.

5. The method of claim 1 , wherein M′ represents a monoatomic cation of an alkali metal selected from a group consisting of Li, K, and Rb, or any combination of such cations.

6. The method of claim 1 , wherein M′ represents a combination of a monoatomic cation of Na with a monoatomic cation of Li, a monoatomic cation of K and/or a monoatomic cation of Rb.

7. The method of claim 1 , wherein M″ represents a trivalent monoatomic cation of a metal selected from a group consisting of Al and Ga, or a combination of such cations.

8. The method of claim 1 , wherein M″ represents a trivalent monoatomic cation of B.

9. The method of claim 1 , wherein M′″ represents a monoatomic cation of an element selected from a group consisting of Si and Ge, or a combination of such cations.

10. The method of claim 1 , wherein M′″ represents a monoatomic cation of an element selected from a group consisting of Al, Ga, N, P, and As, or any combination of such cations.

11. The method of claim 1 , wherein X represents an anion of an element selected from a group consisting of F, Cl, Br, and I, or any combination of such anions.

12. The method of claim 1 , wherein X′ represents an anion of an element selected from a group consisting of O, S, Se, and Te, or any combination of such anions.

13. The method of claim 1 , wherein M″″ represents a cation of an element selected from a group consisting of Ti, V, Cr, Mn, Fe, Co, Ni, Cu, and Zn, or any combination of such cations.

14. The method of claim 1 , wherein the material is selected from a group consisting of (Li,Na)8(Al,Si)6O24(Cl,S)2:Ti (Na,K)8(Al,Si)6O24(Cl,S)2:Ti, and (Na,Rb)8(Al,Si)6O24(Cl,S)2:Ti.

15. The method of claim 1 wherein the material is luminescent with a persistent afterglow period when exposed to light of the first wavelength.

16. The method of claim 1 wherein the step of exposing the material to light of a first wavelength occurs prior to the step of introducing the material into a body fluid or tissue of a human or animal.

17. The method of claim 16 where the step of introducing the material into a body fluid or tissue of a human or animal occurs in vivo during the period of persistent afterglow avoiding the damage caused by materials requiring UV excitation after introduction.

18. The method of claim 17 , wherein the luminescent material is a white light-emitting material.

19. The method of claim 17 , wherein the afterglow period is persistent for at least 50 hours.

20. The method of claim 17 , further comprising capturing an image of the body fluid or tissue of a human or animal during the afterglow period.

21. A medical diagnostic method comprising;
introducing a material to a human or animal, vivo or to a body fluid or tissue sample, wherein the material is represented by the following formula (I)
(M′) 8 (M″M′″) 6 O 24 (X,X′) 2 :M″″   formula (I)

wherein
M′ represents a monoatomic cation of an alkali metal selected from Group 1 of the IUPAC periodic table of the elements, or any combination of such cations;
M″ represents a trivalent monoatomic cation of an element selected from Group 13 of the IUPAC periodic table of the elements, or of a transition element selected from any of Groups 3-12 of the IUPAC periodic table of the elements, or any combi-nation of such cations;
M′″ represents a monoatomic cation of an element selected from Group 14 of the IUPAC periodic table of the elements, or of an element selected from any of Groups 13 and 15 of the IUPAC periodic table of the elements, or of Zn, or any combination of such cations;
X represents an anion of an element selected from Group 17 of the IUPAC periodic table of the elements, or any combination of such anions, or wherein X is absent;
X′ represents an anion of an element selected from Group 16 of the IUPAC periodic table of the elements, or any combination of such anions, or wherein X′ is absent; and
M″″ represents a dopant cation of an element selected from transition metals of the IUPAC periodic table of the elements, or any combination of such cations;

with the proviso that at least one of X and X′ is present; and
exposing the material to light of a first wavelength causing it to emit at least part of the received energy as light at a second wavelength which is longer than the first wavelength.

22. The method of claim 21 , wherein M′ represents a monoatomic cation of an alkali metal selected from Group 1 of the IUPAC periodic table of the elements, or any combination of such cations, with the proviso that M′ does not represent the monoatomic cation of Na alone.

23. The method of claim 21 , wherein M′ represents a combination of at least two monoatomic cations of different alkali metals selected from Group 1 of the IUPAC periodic table of the elements.

24. The method of claim 21 , wherein M′ represents a combination of at least two monoatomic cations of different alkali metals selected from a group consisting of Li, Na, K, and Rb.

25. The method of claim 21 , wherein M′ represents a monoatomic cation of an alkali metal selected from a group consisting of

Assignees

• Turun Yliopisto

Inventors

• Lastusaari Mika
• Norrbo Isabella

Classifications

• C09K11/77344

  Aluminosilicates · CPC title

• G01N21/64

  Fluorescence; Phosphorescence · CPC title

• H10H20/8512

  Wavelength conversion materials · CPC title

• C09K11/646 Primary

  Silicates · CPC title

• A61B5/00 Primary

  Measuring for diagnostic purposes (radiation diagnosis A61B6/00; diagnosis by ultrasonic, sonic or infrasonic waves A61B8/00); Identification of persons · CPC title