Method for preparing oil-dispersible carotenoid preparation

Patent metadata

Field	Value
Publication number	US-10212957-B2
Application number	US-201414902553-A
Country	US
Kind code	B2
Filing date	Jun 3, 2014
Priority date	Jul 9, 2013
Publication date	Feb 26, 2019
Grant date	Feb 26, 2019

Abstract

Disclosed in the present invention is a method for preparing an oil-dispersible carotenoid preparation, comprising (by weight parts): mixing 100 parts of carotenoid microcapsule, 100-400 parts of vegetable oil and 0.1-1 part of oil-soluble antioxidant; and grinding the mixture in a colloid mill in a nitro—gen atmosphere and at 10-30° C. to obtain a uniform oil-dispersible carotenoid preparation, wherein the preparation contains 2%-14% carotenoid with an average particle size of up to 0.1-1 μm, and 100 parts of carotenoid microcapsule contains 10.5-35.8 parts carotenoid, 0.1-1 part of water-soluble antioxidant, and the remainder is a water-soluble colloid. The advantages of the present invention lie in that the oil-dispersible form has a high stability as the surface of the carotenoid particles is still protected with a dense water-soluble colloid, and that an oil-dispersible carotenoid preparation containing carotenoid with a content of up to 2%-14% and an average particle size of only 0.1-1 μm can be prepared.

First claim

The invention claimed is:

1. A method for preparing an oil-dispersible carotenoid preparation, comprising:
mixing 100 parts by weight of carotenoid microcapsule, 100-400 parts by weight of vegetable oil and 0.1-1 part by weight of antioxidant B, and grinding the mixture in a colloid mill in a nitrogen atmosphere at 10-30° C. to obtain a uniform oil-dispersible carotenoid preparation containing carotenoid particles;
wherein an average particle size of the carotenoid is 0.1-1 μm;
wherein the 100 parts by weight of carotenoid microcapsule contains 10.5-35.8 parts by weight carotenoid, 0.1-1 part by weight of antioxidant A and the remaining is a water-soluble colloid;
the antioxidant A is vitamin C, vitamin C sodium, iso-vitamin C or iso-vitamin C sodium;
the antioxidant B is tocopherol, ethoxyquin, BHT or TBHQ; and
wherein a water-soluble colloid protective layer surrounds an outer surface of each of the carotenoid particles.

2. The method for preparing the oil-dispersible carotenoid preparation according to claim 1 , wherein the carotenoid is beta-carotene, astaxanthin, lycopene, canthaxanthin or lutein.

3. The method for preparing the oil-dispersible carotenoid preparation according to claim 1 , wherein the water-soluble colloid is gelatin, octenyl succinic starch ester or Arabic gum.

4. The method for preparing the oil-dispersible carotenoid preparation according to claim 1 , wherein the vegetable oil is soybean oil, corn oil, sunflower seed oil, or peanut oil.

5. An oil-dispersible carotenoid preparation prepared by the method for preparing the oil-dispersible carotenoid preparation according to claim 1 .

6. The method of claim 1 , wherein the oil-dispersible carotenoid preparation is thermally stable for at least 72 hours at 90° C.

7. The method of claim 1 , wherein the average particle size of the carotenoid is 0.1 μm.

8. A method for preparing an oil-dispersible carotenoid preparation, consisting of:
mixing 100 parts by weight of carotenoid microcapsule, 100-400 parts by weight of vegetable oil and 0.1-1 part of antioxidant B, and grinding the mixture in a colloid mill in a nitrogen atmosphere at 10-30° C. to obtain a uniform oil-dispersible carotenoid preparation containing carotenoid particles wherein an average particle size of the carotenoid is 0.1-1 μm;
wherein the 100 parts by weight of carotenoid microcapsule contains 10.5-35.8 parts by weight carotenoid, 0.1-1 part by weight of antioxidant A and the remaining is a water-soluble colloid;
the antioxidant A is vitamin C, vitamin C sodium, iso-vitamin C or iso-vitamin C sodium; the antioxidant B is tocopherol, ethoxyquin, BHT or TBHQ; and
wherein a water-soluble colloid protective layer surrounds an outer surface of each of the carotenoid particles.

Assignees

• Zhejiang New Weipu Additive Co Ltd
• Univ Zhejiang
• Zhejiang Nhu Co Ltd

Inventors

• Qiu Dan
• Shi Lifang
• Li Jiandong
• Chen Zhirong
• Zhou Jiachao

Classifications

• A61P3/02

  Nutrients, e.g. vitamins, minerals · CPC title

• A61K8/31

  Hydrocarbons · CPC title

• A23V2002/00

  Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title

• A61K8/35

  Ketones, e.g. benzophenone · CPC title

• A61Q19/00

  Preparations for care of the skin · CPC title