Carotenoid-containing composition

Patent metadata

Field	Value
Publication number	US-9427010-B2
Application number	US-201313969140-A
Country	US
Kind code	B2
Filing date	Aug 16, 2013
Priority date	Feb 18, 2011
Publication date	Aug 30, 2016
Grant date	Aug 30, 2016

Abstract

A carotenoid-containing composition, comprising: a carotenoid component comprising at least one crystalline carotenoid, at least 90% by mass of the crystalline carotenoid being non-crystalline; a (poly)glycerol fatty acid ester having from 1 to 6 glycerin units and from 1 to 6 fatty acid units and having at least one hydroxyl group from a glycerin unit; and at least one phenolic antioxidant selected from the group consisting of aromatic carboxylic acids, cinnamic acids, and ellagic acids.

First claim

The invention claimed is:

1. A carotenoid-containing, oil-in-water emulsified composition, comprising:
a carotenoid component comprising at least one crystalline carotenoid, at least 90% by mass of the crystalline carotenoid being non-crystalline;
a (poly)glycerol fatty acid ester having from 1 to 6 glycerin units and from 1 to 6 fatty acid units and having at least one hydroxyl group from a glycerin unit; and
at least one phenolic antioxidant selected from the group consisting of aromatic carboxylic acids, cinnamic acids, and ellagic acids,
wherein:
the composition is oil-in-water emulsified;
the crystalline carotenoid is lycopene; and
the (poly)glycerol fatty acid ester has a hydrophilicity-hydrophobicity balance designated by the acronym HLB of 6 or less.

2. The carotenoid-containing, oil-in-water emulsified composition according to claim 1 , wherein the phenolic antioxidant is a cinnamon acid.

3. The carotenoid-containing, oil-in-water emulsified composition according to claim 1 , wherein the phenolic antioxidant is a cinnamon acid; and the cinnamon acid is at least one selected from the group consisting of ferulic acid, γ-orizanol, caffeic acid and chlorogenic acid.

4. The carotenoid-containing, oil-in-water emulsified composition according to claim 1 , further comprising an ascorbic acid-based antioxidant as another antioxidant.

5. The carotenoid-containing, oil-in-water emulsified composition according to claim 1 , wherein the molecular weight of the (poly)glycerol fatty acid ester is 10000 or less.

6. The carotenoid-containing, oil-in-water emulsified composition according to claim 1 , wherein the total mass of the (poly)glycerol fatty acid ester is from 0.01 times to 10 times the total mass of the crystalline carotenoid.

7. The carotenoid-containing, oil-in-water emulsified composition according to claim 1 , wherein the total content of the phenolic antioxidant in the composition is from 1.3 times to 15.0 times the content of the carotenoid component by molar ratio.

8. The carotenoid-containing, oil-in-water emulsified composition according to claim 1 , further comprising an ascorbic acid-based antioxidant as another antioxidant, wherein the total content of the ascorbic acid-based antioxidant in the composition is from 0.6 times to 7.0 times the content of the carotenoid component by molar ratio.

9. The carotenoid-containing, oil-in-water emulsified composition according to claim 1 , wherein each fatty acid of the fatty acid units of the (poly)glycerol fatty acid ester is a fatty acid having a carbon number of from 8 to 22.

10. A method for producing the carotenoid-containing, oil-in-water emulsified composition according to claim 1 , the method comprising:
preparing an oil phase component mixed liquid including the carotenoid component, the (poly)glycerol fatty acid ester and the phenolic antioxidant; and
heating the oil phase component mixed liquid under a condition of a temperature of not less than a dissolution temperature of the carotenoid component.

11. The production method according to claim 10 , wherein a difference between a maximum temperature during the heating and the dissolution temperature of the carotenoid component is 15° C. or less.

12. The production method according to claim 10 , further comprising mixing an oil phase composition obtained from an oil phase component heating process with an aqueous phase composition including an aqueous phase component and performing emulsification.

13. The carotenoid-containing, oil-in-water emulsified composition according to claim 1 , wherein the (poly)glycerol fatty acid ester is selected from the group consisting of glyceryl myristate, glyceryl monostearate, diglyceryl monostearate, tetraglyceryl pentastearate, and hexaglyceryl pentastearate.

Assignees

• Fujifilm Corp

Inventors

• Serizawa Shinichiro

Classifications

• A61P17/00

  Drugs for dermatological disorders · CPC title

• A23L2/52

  Adding ingredients (adding preservatives A23B70/10) · CPC title

• A61K8/498

  having 6-membered rings or their condensed derivatives, e.g. coumarin · CPC title

• A61K8/36

  Carboxylic acids; Salts or anhydrides thereof · CPC title

• A61Q19/00

  Preparations for care of the skin · CPC title