Colon-targeted active agent delivery carrier and uses thereof
US-2024390501-A1 · Nov 28, 2024 · US
US2016338964A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2016338964-A1 |
| Application number | US-201615145373-A |
| Country | US |
| Kind code | A1 |
| Filing date | May 3, 2016 |
| Priority date | Jun 30, 2005 |
| Publication date | Nov 24, 2016 |
| Grant date | — |
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A process for producing a preparation in powder form containing at least one carotenoid. The process contains the following steps: i) suspending one or more carotenoids a) in an aqueous molecular dispersed or colloidal solution of at least one modified starch b) and sucrose c), ii) comminuting the suspended particles, and iii) subsequently converting the suspension optionally in the presence of a coating material into a dry powder; where the suspension contains in process step ii), based on the dry matter of the aqueous suspension, from 1 to 25% by weight of at least one carotenoid, and the ratio of carotenoid a) to sucrose c) is from 1:2 to 1:80 by weight.
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1 - 20 . (canceled) 21 . A process for producing a preparation in powder form., comprising at least one carotenoid, which comprises i) suspending one or more carotenoids a) in an aqueous molecular dispersed or colloidal solution of at least one modified starch b) and sucrose c), ii) comminuting the suspended particles, and iii) subsequently converting the suspension optionally in the presence of a coating material into a dry powder; where the suspension comprises in process step ii), based on the dry matter of the aqueous suspension, from 1 to 25% by weight of at least one carotenoid, and the ratio of carotenoid a) to sucrose c) is from 1:2 to 1:80 by weight. 22 . A process for producing a preparation in powder form, comprising at least one carotenoid, which comprises i) suspending one or more carotenoids a) in an aqueous molecular dispersed or colloidal solution of modified starch b), ii) comminuting the suspended particles, iii) mixing the ground suspension with sucrose c), and iv) subsequently converting the suspension optionally in the presence of a coating material into a dry powder, where the suspension comprises after process step iii), based on the dry matter of the aqueous suspension, from 1 to 25% by weight of at least one carotenoid, and the ratio of carotenoid a) to sucrose c) is from 1:2 to 1:80 by weight. 23 . The process according to claim 21 , wherein the carotenoids a) are compounds selected from the group consisting of β-carotene, lycopene, zeaxanthin, lutein and mixtures thereof. 24 . The process according to claim 22 , wherein the carotenoids a) are compounds selected from the group consisting of β-carotene, lycopene, zeaxanthin, lutein and mixtures thereof. 25 . The process according to claim 21 , wherein the modified starch b) is octenylsuccinate starch. 26 . The process according to claim 22 , wherein the modified starch b) is octenylsuccinate starch. 27 . The process according to claim 22 , which comprises i) suspending one or more carotenoids a) selected from the group consisting of β-carotene, zeaxanthin and lycopene or mixtures thereof in an aqueous molecular or colloidal solution of sodium octenylsuccinate starch b), ii) grinding the suspended particles, and iii) mixing the ground suspension with sucrose c), and iv) subsequently converting the suspension optionally in the presence of a coating material into a dry powder, where the suspension comprises after process step iii), based on. the dry matter of the aqueous suspension, from 8 to 13% by weight of at least one carotenoid a) selected from the group consisting of β-carotene, lutein, zeaxanthin and lycopene or mixtures thereof, and the ratio of carotenoid a) to sucrose c) is from 1.:5 to 1:10 by weight. 28 . The process according to claim 21 , wherein the carotenoids a) are β-carotene. 29 . The process according to claim 27 , wherein the carotenoids a) are β-carotene. 30 . The process according to claim 21 , wherein the carotenoids a) are lycopene. 31 . The process according to claim 27 , wherein the carotenoids a) are lycopene, zeaxanthin, lutein and mixtures thereof. 32 . The process according to claim 21 , wherein the carotenoids a) are zeaxanthin. 33 . The process according to claim 27 , wherein the carotenoids a) are zeaxanthin. 34 . The process according to claim 21 , wherein the carotenoids a) are lutein. 35 . The process according to claim 27 , wherein the carotenoids a) are lutein. 36 . A process for producing an aqueous carotenoid-containing suspension, which comprises i) suspending one or more carotenoids a) in an aqueous molecular dispersed or colloidal solution of at least one modified starch b) and sucrose c), and ii) comminuting the suspended particles, where the suspension comprises after process step ii), based on the dry matter of the aqueous suspension, from 1 to 25% by weight of at least one carotenoid, and the ratio of carotenoid a) to sucrose c) is from 1:2 to 1:80 by weight.
Nutrients, e.g. vitamins, minerals · CPC title
Vitamins A or D · CPC title
using carotenoids or xanthophylls · CPC title
Plant extracts, their artificial duplicates or their derivatives · CPC title
Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin · CPC title
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