Methods for the improved formation of acarbose
US-12351847-B2 · Jul 8, 2025 · US
Genomics of actinoplanes utahensis
US9719064B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9719064-B2 |
| Application number | US-201113814235-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 1, 2011 |
| Priority date | Aug 4, 2010 |
| Publication date | Aug 1, 2017 |
| Grant date | Aug 1, 2017 |
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- Title
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Abstract
Official abstract text for this publication.
The present invention describes the DNA-sequence of the wild type genome as well as all genetic modifications which were introduced into the wild type—and further developed strains, based thereon. Thereby the first genotypic characterization of the developed strains, including the latest production strain, has been accomplished, accounting for the major part of the invention. Furthermore, on the basis of the determined DNA-sequences, potential genes were identified and account, combined with their functional annotation, for another part of the invention. In particular, the gene- and DNA-sequences, as well as protein-sequences derived there out, contribute to the invention which were affected by mutagenic modifications throughout the strain development process, potentially contributing to the increased production yield.
First claim
Opening claim text (preview).
The invention claimed is: 1. A mutated comprising DNA the nucleotide sequence of SEQ ID NO.: 16053 and the mutations shown in the Table below: Position in Nucleotide in Mutated SEQ ID 16053 SEQ ID 16053 Nucleotide 7102 G A 11919 G A 12285 G A 12651 G A 13511 G A 46974 C T 62542 C T 64957 C T 65055 C T 65455 C T/C 65460 C T 65882 G A 72685 A A/G 72693 A A/G 72701 A A/G 73373 C T 73467 C T 76845 C T 78965 C T 80653 G A 85503 G A 88269 G A 88369 G A 89368 C T 89901 C T 90029 C T 91949 C T 93427 C T 101351 G A 103967 C T 104063 C T 110857 C T 112637 G A 114499 G A 115250 G A 115873 C T 115983 C T 117494 C T 119344 G A 134489 C T 139515 C T 146767 C T 161035 G A 172303 G A 176176 G A 178880 G G/A 180754 C T 180925 C T 184674 G A 190568 C T 190644 C T 191971 C T 193584 G A 196028 C T 196338 C T 214992 G A 222841 G A 222924 C T 228543 C T 247200 C T 248952 C T 253299 G A 254551 G A 259829 C T 268705 C T 270822 G A 273723 G A 276430 C T 276561 C T 283007 G A 283062 G A 287132 C T 294767 G A 295356 C T 300028 C T 303810 G A 313837 C T 316698 G A 316929 G A 325503 C T 331088 G A 340040 G A 342987
Assignees
Inventors
Classifications
Preparation of nitrogen-containing carbohydrates · CPC title
- C07K14/365Primary
from Actinoplanes (G) · CPC title
- C12N1/20Primary
Bacteria; Culture media therefor · CPC title
Unicellular algae; Culture media therefor (as new plants A01H13/00) · CPC title
- C12N15/11Primary
DNA or RNA fragments; Modified forms thereof (DNA or RNA not used in recombinant technology, C07H21/00); {Non-coding nucleic acids having a biological activity} · CPC title
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- What does patent US9719064B2 cover?
- The present invention describes the DNA-sequence of the wild type genome as well as all genetic modifications which were introduced into the wild type—and further developed strains, based thereon. Thereby the first genotypic characterization of the developed strains, including the latest production strain, has been accomplished, accounting for the major part of the invention. Furthermore, on th…
- Who is the assignee on this patent?
- Selber Klaus, Weingaertner Bernhard, Wehlmann Hermann, and 6 more
- What technology area does this patent fall under?
- Primary CPC classification C07K14/365. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Aug 01 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 6 related publications on this page (citations in our corpus or others sharing the same primary CPC).