Integrated nucleic acid processing apparatus
US-2022362780-A1 · Nov 17, 2022 · US
US9579644B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9579644-B2 |
| Application number | US-201313867731-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 22, 2013 |
| Priority date | Apr 23, 2012 |
| Publication date | Feb 28, 2017 |
| Grant date | Feb 28, 2017 |
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Official abstract text for this publication.
Pipette for operating a syringe with a bar-shaped housing, a fixture with an opening at the lower end of the housing for putting in a syringe with a fastening portion on the upper edge of a cylinder, a fixture body with a further fixture and a further opening on the lower end of the housing, for putting in a further fastening portion of a piston of the syringe, means for detachably holding the fastening portion in the fixture and the further fastening portion in the further fixture, means for displacing the fixture body within the housing in the longitudinal direction of the housing, which have a draw-up lever activated from the outside of the housing, which is connected to the fixture body via a connection element which grips through a straight slit extending in the longitudinal direction of the housing, wherein below the slit in the housing, a cover stripe covering the slit is held in the housing at two positions spaced apart from each other in the longitudinal direction of the slit, and wherein the connection element has a channel through which the cover stripe extends.
Opening claim text (preview).
The invention claimed is: 1. Pipette for actuating a syringe, comprising: a bar-shaped housing ( 2 ), having housing walls accommodation means ( 20 ) located at a lower end of the housing, for the accommodation of a syringe ( 3 ), the syringe ( 3 ) having a cylinder ( 11 ) and a fastening portion ( 16 ) on the upper end of the cylinder ( 11 ), an accommodation body ( 25 ) with further accommodation means ( 24 ) for the accommodation of a further fastening portion ( 19 ) of a piston ( 12 ) within the syringe ( 3 ), spring fasteners for detachably holding ( 23 , 26 ) the fastening portion ( 16 ) in the accommodation means ( 20 ) and means ( 26 ) for detachably holding the further fastening portion ( 19 ) in the further accommodation means ( 24 ), means for displacing ( 5 , 8 , 34 , 37 , 27 ) the accommodation body ( 25 ) within the housing ( 2 ) in the longitudinal direction of housing ( 2 ), the means for displacing having a draw-up key ( 5 ) actuated from the outside of the housing ( 2 ), and being connected to the accommodation body ( 25 ) via a connection element ( 62 ) which extends through a straight slit ( 4 ) extending in a longitudinal direction of a wall of the housing ( 2 ), characterised in that a cover stripe ( 45 ) is fixedly held within the housing ( 2 ) at two spaced apart positions ( 48 , 49 ) and extends in the longitudinal direction of the slit ( 4 ) and covers the slit ( 4 ) from below, the stripe ( 45 ) extends through a channel ( 50 ) of a portion of the connection element ( 62 ) located within housing ( 2 ), so that slit ( 4 ) is covered from below independent from the position of the draw up key ( 5 ) and the connection element ( 62 ). 2. The pipette according to claim 1 , wherein the friction between the means for displacing ( 5 , 8 , 34 , 37 , 27 ) the accommodation body ( 25 ) and/or other components movable in the housing, which are fixedly connected to the means for displacing, and components fixedly arranged in the housing is dimensioned such that the draw-up key ( 5 ) does not move along the slit ( 4 ) automatically when the pipette is in vertical orientation. 3. The pipette according to claim 2 , wherein the friction between connection element ( 62 ) and covering stripe ( 45 ) is dimensioned such that the draw-up key ( 5 ) does not move along the slit ( 4 ) automatically when the pipette is in vertical orientation, or is correspondingly dimensioned together with the friction between another pair of components movable in the housing ( 2 ) and fixedly arranged in the housing ( 2 ). 4. A pipette according to claim 1 , characterised in that the cover stripe ( 45 ) is flexible. 5. The pipette according to claim 4 , characterised in that the channel ( 50 ) in the connection element ( 62 ) has a flatly U-shaped course in the longitudinal direction of the cover stripe ( 45 ), so that the cover stripe ( 45 ) in the channel ( 50 ) is deflected from a plane in which it runs contiguously to the connection element ( 62 ). 6. A pipette according to claim 1 , characterised in that the channel ( 50 ) in the connection element ( 62 ) runs out curvedly with its mouths into the plane through the deflected portions of the cover stripe ( 45 ). 7. A pipette according to claim 1 , characterised in that the accommodation body ( 25 ) is fixedly connected to at least one support element ( 63 , 64 ), which is supported on a support rally ( 65 , 66 ) in the housing ( 2 ) that is oriented parallel to the plane across the portions of the cover stripe ( 45 ) outside of the connection element ( 62 ). 8. The pipette according to claim 7 , characterised in that the support elements ( 63 , 64 ) are wings which project on different sides of the accommodation body ( 25 ) in a plane that is parallel to the plane in which the cover stripe ( 45 ) is disposed contiguously to the connection element ( 62 ), and which engage in parallel grooves ( 65 , 66 ) on the inner side of opposing walls of the housing ( 2 ). 9. A pipette according to claim 1 , characterised in that the connection element ( 62 ) has a groove stone engaging into the slit ( 4 ). 10. A pipette according to claim 9 , characterised in that the draw-up key carrier ( 29 ) has the groove stone. 11. A pipette according to claim 1 , characterised in that the connection element ( 62 ) has a draw-up key mount ( 28 ) fixedly connected to the accommodation body ( 25 ) and disposed in the housing ( 2 ), as well as a draw-up key carrier ( 29 ), extending through the slit and connected to the draw-up key ( 5 ), wherein the channel ( 50 ) is formed between the draw-up key mount ( 28 ) and the draw-up key carrier ( 29 ). 12. The pipette according to claim 11 , characterised in that one wall of the channel ( 50 ) is a lateral surface ( 51 ) of the draw-up key mount ( 28 ) and an opposing wall of the channel is a further lateral surface ( 52 ) of the draw-up key carrier ( 29 ). 13. The pipette according to claim 12 , characterised in that the draw-up key mount ( 28 ) and the draw-up key carrier ( 29 ) are joined components. 14. A pipette according to claim 1 , characterised in that the cover stripe ( 45 ) is held at two spaced apart positions ( 48 , 49 ) on the two ends and/or outside of the two ends of the slit ( 4 ). 15. A pipette according to claim 1 , characterised in that the cover stripe ( 45 ) is fastened on the housing ( 2 ) beyond the two ends of the slit ( 4 ) in one or plural of the following ways: positive fit, adhesive joining or non-positive fit. 16. The pipette according to claim 15 , characterised in that the cover stripe is fastened on eyes ( 46 , 47 ) or ears on pins ( 48 , 49 ) which project from the inner side of the housing ( 2 ). 17. A pipette according to claim 1 , characterised in that the cover stripe ( 45 ) is elastic in the longitudinal direction and/or tensioned in the longitudinal direction by means of a spring. 18. A pipette according to claim 1 , characterised in that the housing ( 2 ) and the cover stripe ( 45 ) are made of the same plastic material or of different plastic materials. 19. Pipette for actuating a syringe, comprising: a bar-shaped housing ( 2 ), having housing walls accommodation means ( 20 ) located at a lower end of the housing, for the accommodation of a syringe ( 3 ), the syringe ( 3 ) having a cylinder ( 11 ) and a fastening portion ( 16 ) on the upper end of the cylinder ( 11 ), an accommodation body ( 25 ) with a further accommodation means ( 24 ) for the accommodation of a further fastening portion ( 19 ) of a piston ( 12 ) within the syringe ( 3 ), spring fasteners for detachably holding ( 23 , 26 ) the fastening portion ( 16 ) in the accommodation means ( 20 ) and means ( 26 ) for detachably holding the further fastening portion ( 19 ) in the further accommodation means ( 24 ), displacement mechanism ( 5 , 8 , 34 , 37 , 27 ) for displacing the accommodation body ( 25 ) within the housing ( 2 ) in the longitudinal direction of the housing ( 2 ), the displacement mechanism having a draw-up key ( 5 ) actuated from the outside of the housing ( 2 ), and being connected to the accommodation body ( 25 ) via a connection element ( 62 ) which extends through a straight slit ( 4 ) extending in the longitudinal direction of the housing ( 2 ), wherein that below the slit ( 4 ) in the housing ( 2 ), a cover stripe ( 45 ) covering the slit is held in the housing ( 2 ) at two positions ( 48 , 49 ) spaced apart from each other in the longitudinal direction of the slit ( 4 ), and that the connection element ( 62 ) has a channel ( 50 ) t
Ergonomic aspects · CPC title
Repeating pipettes, i.e. for dispensing multiple doses from a single charge · CPC title
Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids · CPC title
Preventing contamination, tampering · CPC title
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