Pressure Sensing Ventricular Assist Devices and Methods of Use

Patent metadata

Field	Value
Publication number	US-2023404421-A1
Application number	US-202318460185-A
Country	US
Kind code	A1
Filing date	Sep 1, 2023
Priority date	Mar 29, 2017
Publication date	Dec 21, 2023
Grant date	—

Abstract

The invention generally relates to heart pump systems. In some embodiments, a pressure sensor is provided with a heart pump, either at the inflow or the outflow of the blood pump. The heart pump may further include a flow estimator based on a rotor drive current signal delivered to the rotor. Based on the rotor drive current signal, a differential pressure across the pump may be calculated. The differential pressure in combination with the pressure measurements from the pressure sensor may be used to calculate pressure on the opposite side of the pump from the pressure sensor. In some embodiments, the pressure sensor is located at the outflow of the pump and the pump is coupled with the left ventricle. The differential pressure and pressure measurement may be used to calculate a left ventricular pressure waveform of the patient. With such a measurement, other physiological parameters may be derived.

First claim

What is claimed is:

1 . A medical system, the system comprising:
an implantable blood pump comprising an inflow configured to be coupled to a left ventricle of a patient and an outflow configured to be coupled to an aorta of the patient; a pulmonary pressure sensor configured to be implanted within a pulmonary artery of the patient; and a controller operably coupled with the blood pump and the pulmonary pressure sensor, the controller configured to:
receive pulmonary pressure measurements from the pulmonary pressure sensor;
determine at least one hemodynamic characteristic of the patient based on the pulmonary pressure measurements; and
adjust a blood pump setting of the implantable blood pump based on the at least one hemodynamic characteristic.

2 . The medical system of claim 1 , wherein the at least one hemodynamic characteristic comprises systolic arterial pressure.

3 . The medical system of claim 1 , wherein the at least one hemodynamic characteristic comprises diastolic arterial pressure.

4 . The medical system of claim 1 , wherein the at least one hemodynamic characteristic comprises mean arterial pressure.

5 . The medical system of claim 1 , wherein the at least one hemodynamic characteristic comprises heart rate.

6 . The medical system of claim 1 , wherein the pulmonary pressure sensor comprises a MEMS based sensor.

7 . The medical system of claim 6 , wherein the pulmonary pressure sensor is wirelessly coupled with the implantable blood pump.

8 . The medical system of claim 6 , wherein the pulmonary pressure sensor is hard wired to the implantable blood pump.

9 . The medical system of claim 1 , wherein the controller is further configured to estimate a left atrial pressure waveform or a left ventricular pressure waveform based on the pulmonary pressure measurements.

10 . The medical system of claim 1 , wherein the controller is configured to adjust a pumping mode of the blood pump in response to the at least one hemodynamic characteristic.

11 . The medical system of claim 1 , wherein the controller is configured to adjust a pump rotor speed in response to the at least one hemodynamic characteristic.

12 . A method for hemodynamic monitoring of a patient with a heart pump, the method comprising:
receiving, with a controller of an implantable blood pump coupled with a heart of a patient, pulmonary pressure measurements from a pulmonary pressure sensor implanted within a pulmonary artery of the patient; determining, with the controller of the implantable blood pump, at least one hemodynamic characteristic of the patient based on the pulmonary pressure measurements; and adjusting a blood pump setting of the implantable blood pump based on the at least one hemodynamic monitoring characteristic.

13 . The method of claim 12 , wherein the at least one hemodynamic characteristic comprises systolic arterial pressure.

14 . The method of claim 12 , wherein the at least one hemodynamic characteristic comprises diastolic arterial pressure.

15 . The method of claim 12 , wherein the at least one hemodynamic characteristic comprises mean arterial pressure.

16 . The method of claim 12 , wherein the at least one hemodynamic characteristic comprises heart rate.

17 . The method of claim 12 , further comprising estimating a left atrial pressure waveform based on the pulmonary pressure measurements.

18 . The method of claim 12 , further comprising estimating a left ventricular pressure waveform based on the pulmonary pressure measurements.

19 . The method of claim 12 , wherein adjusting comprises adjusting a pumping mode of the blood pump in response to the at least one hemodynamic characteristic.

20 . The method of claim 12 , wherein adjusting comprises adjusting a pump rotor speed in response to the at least one hemodynamic characteristic.

Assignees

• Tc1 Llc

Inventors

• Harjes Daniel I
• Frederick Kathryn B
• Lee Eric

Classifications

• A61B5/029 Primary

  Measuring blood output from the heart, e.g. minute volume · CPC title

• A61B5/02405

  Determining heart rate variability · CPC title

• A61M60/148

  in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices · CPC title

• A61M60/88

  Percutaneous cables · CPC title

• A61M60/546 Primary

  of blood flow, e.g. by adapting rotor speed · CPC title