Pressure sensing ventricular assist devices and methods of use

Patent metadata

Field	Value
Publication number	US-10835654-B2
Application number	US-201815939105-A
Country	US
Kind code	B2
Filing date	Mar 28, 2018
Priority date	Mar 29, 2017
Publication date	Nov 17, 2020
Grant date	Nov 17, 2020

Abstract

The invention generally relates to heart pump systems. In some embodiments, a pressure sensor is provided with a heart pump, either at the inflow or the outflow of the blood pump. The heart pump may further include a flow estimator based on a rotor drive current signal delivered to the rotor. Based on the rotor drive current signal, a differential pressure across the pump may be calculated. The differential pressure in combination with the pressure measurements from the pressure sensor may be used to calculate pressure on the opposite side of the pump from the pressure sensor. In some embodiments, the pressure sensor is located at the outflow of the pump and the pump is coupled with the left ventricle. The differential pressure and pressure measurement may be used to calculate a left ventricular pressure waveform of the patient. With such a measurement, other physiological parameters may be derived.

First claim

What is claimed is:

1. A blood pump system, the system comprising:
a blood pump comprising an inflow and an outflow,
a pressure sensor coupled with the outflow or the inflow of the blood pump;
a controller operably coupled with the blood pump and the pressure sensor, the controller configured to:
determine a differential pressure across the blood pump based on a rotor drive current signal configured to drive the blood pump;
calculate, with the differential pressure across the blood pump: 1) a pressure at the inflow of the blood pump when the pressure sensor is at the outflow, or 2) a pressure at the outflow of the blood pump when the pressure sensor is at the inflow; and
generate a desired data waveform from the calculated pressure.

2. The blood pump system of claim 1 , wherein the controller is configured to output the calculated data waveform.

3. The blood pump system of claim 1 , wherein the controller is configured to adjust a pumping of the blood pump in response to the calculated data waveform.

4. The blood pump system of claim 1 , wherein the controller is configured to adjust a pumping mode of the blood pump in response to the calculated data waveform.

5. The blood pump system of claim 1 , wherein the controller adjusts a pump rotor speed in response to the calculated data waveform.

6. The blood pump system of claim 1 , wherein the pressure sensor is integrated into a housing of the blood pump at the outflow of the blood pump.

7. The blood pump system of claim 1 , wherein the pressure sensor is positioned within an outflow graft coupled to the blood pump.

8. The blood pump system of claim 1 , wherein the pressure sensor is positioned within an inlet cannula of the blood pump.

9. The blood pump system of claim 1 , wherein the controller determines the differential pressure across the blood pump by accessing a lookup table associating rotor drive current signal values with differential pressure.

10. The blood pump system of claim 1 , wherein the desired data waveform comprises a left ventricular pressure waveform and wherein the left ventricular pressure waveform is calculated by subtracting the differential pressure from the calculated pressure.

11. The blood pump system of claim 1 , further comprising a pulmonary pressure sensor configured to be implanted within a pulmonary artery of a patient, wherein the controller is further configured to:
receive pulmonary pressure measurements from the pulmonary pressure sensor; and
estimate a left atrial pressure waveform or a left ventricular pressure waveform based on the pulmonary pressure measurements.

12. A method for hemodynamic monitoring of a patient with a heart pump, the method comprising:
determining a differential pressure measurement across the heart pump having an inflow and an outflow based on a rotor drive current signal configured to drive the heart pump;
receiving a pressure measurement from a pressure sensor positioned in the outflow or the inflow of the heart pump; and
calculating a desired data waveform based on the differential pressure and the pressure measurement.

13. The method of claim 12 , comprising outputting the desired data waveform to a clinician.

14. The method of claim 12 , further comprising adjusting a pump operation based on the calculated desired data waveform.

15. The method of claim 12 , wherein the heart pump is configured to be coupled with a right ventricle of the patient, and wherein the desired data waveform comprises a right ventricular pressure waveform.

16. The method of claim 12 , wherein the heart pump is configured to be coupled with a left atrium of the patient, and wherein the desired data waveform comprises a left atrial pressure waveform.

17. The method of claim 12 , wherein the heart pump is configured to be coupled with a left ventricle of the patient, and wherein the desired data waveform comprises a left ventricular pressure waveform.

18. The method of claim 12 , wherein determining the differential pressure comprises accessing a lookup table associating rotor drive current signal values with differential pressures.

19. The method of claim 12 , wherein the pressure sensor is integrated within a pump housing of the pump.

20. The method of claim 12 , wherein the pressure sensor is positioned within the outflow of the heart pump.

21. The method of claim 20 , wherein the pressure sensor is positioned within an outflow graft coupled with the heart pump.

22. The method of claim 12 , wherein the pressure sensor is positioned within the inflow of the heart pump.

Assignees

• Tc1 Llc

Inventors

• Harjes Daniel I
• Frederick Kathryn B
• Lee Eric

Classifications

• A61B5/029 Primary

  Measuring blood output from the heart, e.g. minute volume · CPC title

• A61M60/88

  Percutaneous cables · CPC title

• A61M60/546 Primary

  of blood flow, e.g. by adapting rotor speed · CPC title

• A61M60/531

  using blood pressure data, e.g. from blood pressure sensors · CPC title

• A61M60/422

  the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps · CPC title