Chinese herbal medicine composition having a function of relieving hypothyroidism, preparation method and use thereof

Patent metadata

Field	Value
Publication number	US-2018369308-A1
Application number	US-201816015660-A
Country	US
Kind code	A1
Filing date	Jun 22, 2018
Priority date	Jun 26, 2017
Publication date	Dec 27, 2018
Grant date	—

Abstract

The present disclosure relates to the field of health care product and food technology, disclosing a Chinese herbal medicine composition having a function of relieving hypothyroidism, and preparation method and use thereof. The Chinese herbal medicine composition described in the present disclosure, in parts by weight, comprises: 10 to 100 parts of GINSENG RADIX ET RHIZOMA, 10 to 100 parts of LYCII FRUCTUS, and 6 to 60 parts of CINNAMOMI CORTEX. The Chinese herbal medicine composition described in the present disclosure adopts GINSENG RADIX ET RHIZOMA, LYCII FRUCTUS and CINNAMOMI CORTEX as starting materials, creates synergistic effects through rational combination. Experiments indicate that the Chinese herbal medicine composition described in the present disclosure can improve functions of the thyroid gland in rat hypothyroidism model, reduce serum VEGF level in the model, showing a function of relieving hypothyroidism and protecting the thyroid gland.

First claim

What is claimed is:

1 . A Chinese herbal medicine composition, in parts by weight, comprising 10 to 100 parts of GINSENG RADIX ET RHIZOMA, 10 to 100 parts of LYCII FRUCTUS, and 6 to 60 parts of CINNAMOMI CORTEX.

2 . The composition according to claim 1 , wherein, in parts by weight, the composition is made from 20 to 80 parts of GINSENG RADIX ET RHIZOMA, 20 to 80 parts of LYCII FRUCTUS, and 12 to 48 parts of CINNAMOMI CORTEX.

3 . The composition according to claim 1 , wherein, in parts by weight, the composition is made from 30 to 70 parts of GINSENG RADIX ET RHIZOMA, 30 to 70 parts of LYCII FRUCTUS, and 18 to 42 parts of CINNAMOMI CORTEX.

4 . A method for preparing the composition according to claim 1 , comprising:
mixing GINSENG RADIX ET RHIZOMA, LYCII FRUCTUS and CINNAMOMI CORTEX as starting materials, extracting by adding water, and filtering and collecting the extract.

5 . The method according to claim 4 , wherein the weight of the added water is 8 to 12 times the weight of the starting materials.

6 . The method according to claim 4 , wherein the temperature of the extraction is 100° C., the duration of the extraction is 1.5 h to 2.5 h, the times of the extraction is 2 to 3.

7 . The method according to claim 4 , further comprising a concentration step, wherein the concentration is conducted by concentrating the extract 8 to 12 folds.

8 . A method for relieving hypothyroidism and/or protecting functions of the thyroid gland, comprising administering the composition according to claim 1 to a subject in need thereof.

9 . The composition according to claim 1 , which is in the form of a health care product.

10 . The composition according to claim 9 , which is in the form of a solid preparation or a liquid preparation; wherein
the solid preparation is a tablet, a capsule, a granule, a pill, a dropping pill, a mixture or a power preparation; and the liquid preparation is an oral liquid, a soft capsule or an aerosol preparation.

Assignees

• Infinitus China Co Ltd

Inventors

• Xiao Lingyun
• Cong Renhuai
• Hu Minghua
• Wang Yuanyuan
• Ma Fangli
• Ma Chung Wah

Classifications

• A61P5/14

  of the thyroid hormones, e.g. T3, T4 · CPC title

• A61K36/258 Primary

  Panax (ginseng) · CPC title

• A61K2236/331

  using water, e.g. cold water, infusion, tea, steam distillation or decoction · CPC title

• A61K36/54

  Lauraceae (Laurel family), e.g. cinnamon or sassafras · CPC title

• A61K36/815

  Lycium (desert-thorn) · CPC title