Topical compositions comprising fermented extracts of traditional chinese medicinal (TCM) ingredients, and methods of making and using same

Patent metadata

Field	Value
Publication number	US-9327004-B2
Application number	US-201314043021-A
Country	US
Kind code	B2
Filing date	Oct 1, 2013
Priority date	Mar 11, 2009
Publication date	May 3, 2016
Grant date	May 3, 2016

Abstract

The present invention relates to topical compositions containing fermented extracts of Traditional Chinese Medicinal (TCM) ingredients for improving the appearance and skin condition of the user. The topical compositions of the present invention are tailored for different users of different skin compositions according to TCM principles. The fermented TCM extracts are characterized by reduced odor and/or color in comparison with unfermented TCM extracts and are therefore more suitable for use in cosmetic products.

First claim

What we claim is:

1. A topical composition for restoring Yin-Yang balance of skin of a person with Yin-dominant or balanced-to-Yin skin, said composition comprising an effective amount of a blend of fermented extracts of an effective amount of Rhodiola rosea rhizome, Perilla frutescens fruit, Phellodendron amurense bark, and Foeniculum vulgare seed, Santalum album stem, Hordeum distichon seed, and Citrus reticulata peel, wherein said blend of fermented extracts is obtained by:
(i) blending Rhodiola rosea rhizome, Perilla frutescens fruit, Phellodendron amurense bark, and Foeniculum vulgare seed, Santalum album stem, Hordeum distichon seed, and Citrus reticulata peel to provide a blend of plants parts;
(ii) fermenting the blend of plant parts with a microorganism, wherein the microorganism is yeast cells, and culturing nutrients; or
(iii) fermenting the blend of plant parts with microorganisms, wherein said microorganisms are yeast cells, in an aqueous environment in substantial absence of additional nutrients in a low nutrient media to catabolically process the blend of plant parts;
(iv) monitoring the fermentation of (ii) or (iii) for signs of plateauing biological activity;
(v) briefly raising the temperature to rupture the yeast cells to release yeast cell contents, or disrupting the yeast cells by sonication; and
(vi) filtering to remove yeast cell debris and to recover the blend of fermented extracts, wherein the blend of fermented extract has reduced odor and/or color, wherein the blend of fermented extracts is in the form of a fine powder, and wherein the topical composition further comprises a cosmetically or pharmaceutically acceptable carrier.

Assignees

• Cheng Jing
• Chen Chia-Wen
• Schnittger Steven Francis
• Lu Ming
• Elc Man Llc

Inventors

• Cheng Jing
• Chen Chia-Wen
• Schnittger Steven Francis
• Lu Ming

Classifications

• A61P17/10

  Anti-acne agents · CPC title

• A61P17/00

  Drugs for dermatological disorders · CPC title

• A61K2800/59

  Mixtures · CPC title

• A61K36/804

  Rehmannia · CPC title

• A61K36/258

  Panax (ginseng) · CPC title