Manuka honey microneedle
US-11904125-B2 · Feb 20, 2024 · US
US2018078584A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2018078584-A1 |
| Application number | US-201615561178-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jun 24, 2016 |
| Priority date | Jul 30, 2015 |
| Publication date | Mar 22, 2018 |
| Grant date | — |
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A Chinese medicine extract and preparation method and application thereof. Raw materials of the extract are Artemisia carvifolia and propolis. The extract has an excellent effect of inhibiting CaN-NF-AT pathway and a lower relative toxicity for cells.
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1 . A Chinese medicine extract which is prepared from Artemisia carvifolia and propolis. 2 . The Chinese medicine extract according to claim 1 , wherein the mass ratio of Artemisia carvifolia to propolis is 3:5 to 5:3. 3 . A method for preparing the Chinese medicine extract according to claim 1 , comprising extracting Artemisia carvifolia and propolis. 4 . The method according to claim 3 , wherein a solvent for extraction is one of the group consisting of alcohols, alkanes, chloroform, acetone, water and ethyl acetate, or a mixture thereof. 5 . The method according to claim 3 , wherein the extraction method is percolation, impregnation, decoction, reflux extraction, continuous reflux extraction, supercritical fluid extraction or ultrasound extraction. 6 . A method for inhibiting CaN-NF-AT pathway, treating skin inflammations, treating autoimmune diseases, skin relax or anti-allergy in a subject in need thereof comprising administering to the subject a therapeutically effective amount of the Chinese medicine extract of claim 1 . 7 . (canceled) 8 . A medicament for treating skin inflammations or autoimmune diseases or a cosmetic for skin relax and anti-allergy, comprising the Chinese medicine extract of claim 1 . 9 - 10 . (canceled)
involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones · CPC title
Angiosperms [Magnoliophyta] · CPC title
Immunomodulators · CPC title
Artemisia, e.g. wormwood or sagebrush · CPC title
Honey; Royal jelly, Propolis · CPC title
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