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Composition comprising scirpusin a and scirpusin b and anti-obesity potential thereof
US2017072003A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2017072003-A1 |
| Application number | US-201615213655-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jul 19, 2016 |
| Priority date | Jul 18, 2012 |
| Publication date | Mar 16, 2017 |
| Grant date | — |
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Abstract
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Disclosed are methods of managing hypercholesterolemia using a composition of matter comprising the ethyl acetate fraction of the extract of Cyperus rotundus rhizomes standardized to contain 5% of total stilbenes.
First claim
Opening claim text (preview).
We claim: 1 . A method of treating hypercholesterolemia in humans, said method comprising step of administering to said humans orally twice a day, composition comprising the ethyl acetate fraction of the extract of Cyperus rotundus rhizomes standardized to contain 5% of total stilbenes to achieve the effects of (a) reduction in the systemic levels of total cholesterol, Low Density Lipoproteins (LDL), Very Low Density Lipoproteins (VLDL) and serum triglycerides and (b) enhancement in the systemic levels of High Density Lipoproteins (HDL). 2 . The method according to claim 1 wherein the composition comprising the ethyl acetate fraction of the extract of Cyperus rotundus rhizomes standardized to contain 5% of total stilbenes consists essentially of piceatannol and dimers thereof. 3 . The method according to claim 2 wherein the composition comprising the ethyl acetate fraction of the extract of Cyperus rotundus rhizomes standardized to contain 5% of total stilbenes, consists essentially of a combination of piceatannol, scirpusin B and scirpusin A. 4 . A method of treating hypercholesterolemia in humans, said method comprising step of administering to said humans orally twice a day, composition comprising the ethyl acetate fraction of the extract of Cyperus rotundus rhizomes standardized to contain greater than 3% of total stilbenes to achieve the effects of (a) reduction in the systemic levels of total cholesterol, Low Density Lipoproteins (LDL), Very Low Density Lipoproteins (VLDL) and serum triglycerides and (b) enhancement in the systemic levels of High Density Lipoproteins (HDL). 5 . The method according to claim 4 wherein the composition comprising the ethyl acetate fraction of the extract of Cyperus rotundus rhizomes standardized to contain greater than 3% of total stilbenes consists essentially of piceatannol and dimers thereof. 6 . The methods according to claim 5 wherein the composition comprising the ethyl acetate fraction of the extract of Cyperus rotundus rhizomes standardized to contain greater than 3% of total stilbenes, consists essentially of a combination of piceatannol, scirpusin B and scirpusin A.
Assignees
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Classifications
condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone · CPC title
carbocyclic · CPC title
- A61K36/8905Primary
Cyperus (flatsedge) · CPC title
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- What does patent US2017072003A1 cover?
- Disclosed are methods of managing hypercholesterolemia using a composition of matter comprising the ethyl acetate fraction of the extract of Cyperus rotundus rhizomes standardized to contain 5% of total stilbenes.
- Who is the assignee on this patent?
- Majeed Muhammed, Nagabhushanam Kalyanam, Kalman Douglas, and 5 more
- What technology area does this patent fall under?
- Primary CPC classification A61K36/8905. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Thu Mar 16 2017 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).