Composition comprising scirpusin A and scirpusin B and anti-obesity potential thereof
US-10172903-B2 · Jan 8, 2019 · US
Process and compositions for enhancing energy expenditure
US11925671B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11925671-B2 |
| Application number | US-202117151124-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 16, 2021 |
| Priority date | Jan 17, 2020 |
| Publication date | Mar 12, 2024 |
| Grant date | Mar 12, 2024 |
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- Title
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Abstract
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The invention discloses a composition comprising Cyperus rotundus extract and Passiflora edulis extract comprising piceatannol, scirpusin B, scirpusin A, cyperusphenol A and cyperusphenol B, standardized to contain 6-10% w/w total stilbenes. The invention also discloses the use of the above mentioned composition in enhancing energy expenditure in mammalian adipose cellular systems by the conversion of white adipose tissues to brown adipose tissues, inhibition of adipogenesis and for preventing weight gain in mammals.
First claim
Opening claim text (preview).
We claim: 1. A method of enhancing energy expenditure in adipose cellular systems of a mammal, said method comprising a) identifying a mammal requiring increase in energy expenditure, and b) administering a composition comprising Cyperus rotundus extract and Passiflora edulis extract comprising Piceatannol, Scirpusin B, Scirpusin A, Cyperusphenol A and Cyperusphenol B, standardized to contain 6-10% w/w total stilbenes to achieve effects of (a) increased expression of PRDM16, PGC-1α and BMP7, (b) induce brown or beige or brite phenotype in white adipocyte depots, or (c) induce enhanced expression of mitochondrial uncoupling protein-1 to result in increased mitochondrial thermogenesis in differentiated brown adipocytes and beige or brite adipocytes. 2. The method as in claim 1 , wherein mammals requiring enhanced energy expenditure is-selected from the group consisting of mammals in need of cold thermogenesis and increased endurance during physical activity and mammals with obesity. 3. A method of inhibition of adipogenesis in mammalian cellular systems, said method comprising step of bringing into contact mammalian adipocytes with a composition comprising Cyperus rotundus extract and Passiflora edulis extract comprising Piceatannol, Scirpusin B, Scirpusin A, Cyperusphenol A and Cyperusphenol B, standardized to contain 6-10% w/w total stilbenes to bring about inhibition in adipogenesis.
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Classifications
Magnoliopsida (dicotyledons) · CPC title
- A61K31/05Primary
Phenols {(cannabinoids A61K31/658)} · CPC title
- A61K36/8905Primary
Cyperus (flatsedge) · CPC title
condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone · CPC title
Anorexiants; Antiobesity agents · CPC title
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- What does patent US11925671B2 cover?
- The invention discloses a composition comprising Cyperus rotundus extract and Passiflora edulis extract comprising piceatannol, scirpusin B, scirpusin A, cyperusphenol A and cyperusphenol B, standardized to contain 6-10% w/w total stilbenes. The invention also discloses the use of the above mentioned composition in enhancing energy expenditure in mammalian adipose cellular systems by the co…
- Who is the assignee on this patent?
- Majeed Muhammed, Nagabhushanam Kalyanam, Mundkur Lakshmi, and 1 more
- What technology area does this patent fall under?
- Primary CPC classification A61K31/05. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Mar 12 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).