Method for preparing pyrrolo[3,2,-d]pyrimidine compound, and intermediates thereof
US-2020239484-A1 · Jul 30, 2020 · US
US12358928B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12358928-B2 |
| Application number | US-202318232435-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 10, 2023 |
| Priority date | Feb 5, 2016 |
| Publication date | Jul 15, 2025 |
| Grant date | Jul 15, 2025 |
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The present disclosure relates generally to compounds and compositions, and their use as kinase inhibitors.
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The invention claimed is: 1. A compound, or a pharmaceutically acceptable salt, tautomer, stereoisomer or mixture of stereoisomers thereof, that is chosen from: No. Structure 38A 38B 200 2. A pharmaceutical composition comprising a compound or a pharmaceutically acceptable salt, tautomer, stereoisomer or mixture of stereoisomers thereof of claim 1 , and a pharmaceutically acceptable excipient. 3. A compound having the structure: or a tautomer, stereoisomer or a mixture of stereoisomers thereof, or a pharmaceutically acceptable salt thereof. 4. A pharmaceutical composition comprising a compound of claim 3 or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient. 5. The compound according to claim 1 , having the structure: or a tautomer, stereoisomer or a mixture of stereoisomers thereof, or a pharmaceutically acceptable salt thereof. 6. A pharmaceutical composition comprising a compound of claim 5 or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient. 7. The compound according to claim 1 , compound having the structure: or a tautomer, stereoisomer or a mixture of stereoisomers thereof, or a pharmaceutically acceptable salt thereof. 8. A pharmaceutical composition comprising a compound of claim 7 or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.
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