Water soluble compositions comprising purified cannabinoids

Patent metadata

Field	Value
Publication number	US-12324801-B2
Application number	US-202117352071-A
Country	US
Kind code	B2
Filing date	Jun 18, 2021
Priority date	Aug 29, 2016
Publication date	Jun 10, 2025
Grant date	Jun 10, 2025

Abstract

This disclosure relates to new compositions and methods for making cannabinoid formulations. In one embodiment, this disclosure provides water soluble compositions comprising a first purified cannabinoid and Vitamin E TPGS. In one embodiment, the disclosure herein comprises a method of making powders comprising heatings material to a first temperature and a second temperature.

First claim

What is claimed:

1. A liquid composition, comprising:
one or more purified cannabinoids selected from the group consisting of D9-THC, D8-THC, THCA, THCV, D8-THCV, D9-THCV, THCVA, CBD, CBDA, CBDV, CBDVA, CBC, CBCA, CBCV, CBCVA, CBG, CBGA, CBGV, CBGVA, CBN, CBNA, CBNV, CBNVA, CBND, CBNDA, CBNDV, CBNDVA, CBE, CBEA, CBEV, CBEVA, CBL, CBLA, CBLV, and CBLVA;
Vitamin E TPGS; and
water,
wherein the liquid composition comprises a ratio of total purified cannabinoid content to Vitamin E TPGS of about 1:1 to about 1:10 based on mass percent.

2. The liquid composition of claim 1 , wherein the liquid composition comprises a ratio of total purified cannabinoid content to Vitamin E TPGS of about 1:1 to about 1:8.

3. The liquid composition of claim 1 , wherein the liquid composition comprises a ratio of total purified cannabinoid content to Vitamin E TPGS of about 1:1 to about 1:6.

4. The liquid composition of claim 1 , wherein the liquid composition comprises a ratio of total purified cannabinoid content to Vitamin E TPGS of about 1:1 to about 1:4.

5. The liquid composition of claim 1 , wherein the liquid composition comprises a ratio of total purified cannabinoid content to Vitamin E TPGS of about 1:1 to about 1:2.

6. The liquid composition of claim 1 , wherein the one or more purified cannabinoids comprise THCA, CBC, THC, CBN, CBD, CBG, CBGA, CBDA, or a combination thereof.

7. The liquid composition of claim 1 , wherein the one or more purified cannabinoids comprise CBD, THC, or a combination thereof.

8. The liquid composition of claim 1 , wherein the one or more purified cannabinoids comprise a combination of THC and CBD.

9. The liquid composition of claim 1 , further comprising one or more purified terpenes.

10. The liquid composition of claim 9 , wherein the one or more purified terpenes is Alpha-terpineol, Bergamotene (a-cis-Bergamotene) (a-trans-Bergamotene), Bisabolol (13-Bisabolol), Borneol, Camphor, Capsaicin, Carvacrol, Caryophyllene (13-Caryophyllene), Caryophyllene oxide, Cineole, Cinnamaldehyde (a-amyl-Cinnamaldehyde) (a-hexyl-Cinnamaldehyde), Cinnamyl Alcohol, Citronella!, Citronellol, Ethyl, Cinnamate, Eucalyptol/1,8-Cineole, Farnesol, Fenchel (13-Fenchol), Geranyl acetate, Germacrene B, Guaiene (a-Guaiene), Humulene (a-Humulene) (13-Humulene), lonol (3-oxo-a-ionol) (13-lonol), lonone (a-lonone) (13-lonone), Isoamyl acetate, Isoprene, Kahweol, Laevo-Carvone, Lavandulol, Limonene, Linalool, Linalyl acetate, Luteolin, Lycopene, Menthol, Myrcene (13-Myrcene), Nerol, Nerolidol, Neryl acetate, P-cymene, Phytol, Pinene, Pristimerin, Retinol, Terpin hydrate, Terpineol, Terpinol-4-ol, Terpinolene, Thujone, Thymol, or Vanillin.

11. The liquid composition of claim 1 , wherein the liquid composition is a juice, a soft drink, a wine, a cocktail, a medicinal preparation, coffee, or tea.

12. A liquid composition, comprising:
a first purified cannabinoid selected from the group consisting of D9-THC, D8-THC, THCA, THCV, D8-THCV, D9-THCV, THCVA, CBD, CBDA, CBDV, CBDVA, CBC, CBCA, CBCV, CBCVA, CBG, CBGA, CBGV, CBGVA, CBN, CBNA, CBNV, CBNVA, CBND, CBNDA, CBNDV, CBNDVA, CBE, CBEA, CBEV, CBEVA, CBL, CBLA, CBLV, and CBLVA;
Vitamin E TPGS; and
water,
wherein the liquid composition comprises a ratio of the first purified cannabinoid content to Vitamin E TPGS of about 1:1 to about 1:10 based on mass percent.

13. A liquid composition, comprising:
one or more purified cannabinoids;
Vitamin E TPGS; and water,
wherein the liquid composition comprises a ratio of total purified cannabinoid content to Vitamin E TPGS of about 1:1 to about 1:10 based on mass percent and the liquid composition does not comprise a TPGS coprecipitate.

14. The liquid composition of claim 13 , wherein the liquid composition comprises a ratio of total purified cannabinoid content to Vitamin E TPGS of about 1:1 to about 1:8.

15. The liquid composition of claim 13 , wherein the liquid composition comprises a ratio of total purified cannabinoid content to Vitamin E TPGS of about 1:1 to about 1:6.

16. The liquid composition of claim 13 , wherein the liquid composition comprises a ratio of total purified cannabinoid content to Vitamin E TPGS of about 1:1 to about 1:4.

17. The liquid composition of claim 13 , wherein the liquid composition comprises a ratio of total purified cannabinoid content to Vitamin E TPGS of about 1:1 to about 1:2.

18. The liquid composition of claim 13 , wherein the one or more purified cannabinoids comprise THCA, CBC, THC, CBN, CBD, CBG, CBGA, CBDA, or a combination thereof.

19. The liquid composition of claim 13 , wherein the one or more purified cannabinoids comprise CBD, THC, or a combination thereof.

20. The liquid composition of claim 13 , wherein the one or more purified cannabinoids comprise a combination of THC and CBD.

21. The liquid composition of claim 13 , further comprising one or more purified terpenes.

22. The liquid composition of claim 21 , wherein the one or more purified terpenes is Alpha-terpineol, Bergamotene (a-cis-Bergamotene) (a-trans-Bergamotene), Bisabolol (13-Bisabolol), Borneol, Camphor, Capsaicin, Carvacrol, Caryophyllene (13-Caryophyllene), Caryophyllene oxide, Cineole, Cinnamaldehyde (a-amyl-Cinnamaldehyde) (a-hexyl-Cinnamaldehyde), Cinnamyl Alcohol, Citronella!, Citronellol, Ethyl, Cinnamate, Eucalyptol/1,8-Cineole, Farnesol, Fenchel (13-Fenchol), Geranyl acetate, Germacrene B, Guaiene (a-Guaiene), Humulene (a-Humulene) (13-Humulene), lonol (3-oxo-a-ionol) (13-lonol), lonone (a-lonone) (13-lonone), Isoamyl acetate, Isoprene, Kahweol, Laevo-Carvone, Lavandulol, Limonene, Linalool, Linalyl acetate, Luteolin, Lycopene, Menthol, Myrcene (13-Myrcene), Nerol, Nerolidol, Neryl acetate, P-cymene, Phytol, Pinene, Pristimerin, Retinol, Terpin hydrate, Terpineol, Terpinol-4-ol, Terpinolene, Thujone, Thymol, or Vanillin.

23. The liquid composition of claim 13 , wherein the liquid composition is a juice, a soft drink, a wine, a cocktail, a medicinal preparation, coffee, or tea.

Assignees

• Canopy Growth Corp

Inventors

• Levy Kurt Aron

Classifications

• A61K36/3482

  Cannabis · CPC title

• A61K31/658

  o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol · CPC title

• A61K31/355

  Tocopherols, e.g. vitamin E · CPC title

• A61K31/065

  Diphenyl-substituted acyclic alcohols · CPC title

• A61K31/105

  Persulfides (thiuram disulfides A61K31/145; thiosulfonic acids A61K31/185) · CPC title