Water soluble compositions comprising purified cannabinoids

Patent metadata

Field	Value
Publication number	US-10568865-B2
Application number	US-201716328833-A
Country	US
Kind code	B2
Filing date	Aug 29, 2017
Priority date	Aug 29, 2016
Publication date	Feb 25, 2020
Grant date	Feb 25, 2020

Abstract

This disclosures relates to new compositions and methods for making cannabinoid formulations. In one embodiment, this disclosure provides water soluble compositions comprising a first purified cannabinoid and Vitamin E TPGS. In one embodiment, the disclosure herein comprises a method of making powders comprising heatings material to a first temperature and a second temperature.

First claim

What is claimed is:

1. A water-soluble powder composition, comprising:
one or more purified cannabinoids;
a purified terpene; and
Vitamin E TPGS.

2. The composition of claim 1 , comprising a ratio of Vitamin E TPGS to the one or more purified cannabinoids of about 85:15 to about 75:25 by percent mass.

3. The composition of claim 1 , comprising a ratio of Vitamin E TPGS to the one or more purified cannabinoids of about 82:18 to about 78:22 by percent mass.

4. The composition of claim 1 , comprising between 0-1% water by mass percent.

5. The composition of claim 4 , comprising between 0-0.5% water by mass percent.

6. The composition of claim 1 , wherein the one or more purified cannabinoids is Cannabidiol (CBD), Tetrahydrocannabinol (THC), Tetrahydrocannabivarin (THCV) or a combination thereof.

7. The composition of claim 6 , wherein the composition comprises the combination of THC, CBD and THCV.

8. The composition of claim 1 , wherein the purified terpene is linalool, alpha-pinene, alpha-humulene, terpinolene, eucalyptol, pulegone, terpineol, beta-caryophyllene, cymene or combinations thereof.

9. The composition of claim 7 , wherein the composition comprises the combination of beta-caryophyllene, linalool, and cymene as purified terpenes.

10. A method of making a water soluble powder comprising a first purified cannabinoid and a purified terpene, the method comprising:
separating a first purified cannabinoid and a purified terpene from a cannabis plant material;
combining the first purified cannabinoid and the purified terpene to form a cannabis oil;
adding the cannabis oil and Vitamin E TPGS to water to create an aqueous cannabinoid formulation;
sonicating the aqueous cannabinoid formulation; and
removing the water from the aqueous cannabinoid formulation to create a water soluble powder.

11. The method of claim 10 , wherein removing the water from the aqueous cannabinoid formulation comprises freeze-drying the aqueous cannabinoid formulation.

12. The method of claim 11 , further comprising heating the freeze-dried aqueous cannabinoid formulation to a temperature between 70-90° C.

13. The method of claim 10 , wherein the aqueous cannabinoid formulation comprises a ratio of Vitamin E TPGS to the first purified cannabinoid of about 85:15 to about 75:25 by percent mass.

14. The method of claim 10 , wherein the aqueous cannabinoid formulation comprises a ratio of Vitamin E TPGS to the first purified cannabinoid of about 82:18 to about 78:22 by percent mass.

Assignees

• Canopy Growth Corp

Inventors

• Levy Kurt Aron

Classifications

• A61K45/06

  Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca · CPC title

• A61K31/065

  Diphenyl-substituted acyclic alcohols · CPC title

• A61K31/353 Primary

  3,4-Dihydrobenzopyrans, e.g. chroman, catechin · CPC title

• A61K31/105

  Persulfides (thiuram disulfides A61K31/145; thiosulfonic acids A61K31/185) · CPC title

• A61K9/08

  Solutions {(composition of solutions A61K47/00)} · CPC title