Injection device for drug delivery and packaging for the injection device

Patent metadata

Field	Value
Publication number	US-12059555-B2
Application number	US-202017009868-A
Country	US
Kind code	B2
Filing date	Sep 2, 2020
Priority date	Sep 3, 2019
Publication date	Aug 13, 2024
Grant date	Aug 13, 2024

Abstract

An injection device is provided, including a syringe having a barrel and a flange and a backstop configured to be coupled with the syringe adjacent to the flange. The backstop includes an inner surface generally extending around at least a portion of the syringe, wherein the inner surface includes at least one protrusion extending away from the inner surface and configured to engage the flange and/or the barrel to permit or promote airflow through a space between the inner surface and the syringe.

First claim

What is claimed is:

1. An injection device comprising:
a syringe having a barrel and a flange; and
a backstop configured to be coupled with the syringe adjacent to the flange during use of the syringe for drug delivery, the backstop having an inner surface including a C-shaped portion extending around at least a portion of a circumference of the syringe for an entire length of the C-shaped portion, wherein the C-shaped portion of the inner surface is interrupted by an opening that permits the backstop to receive the flange and/or the barrel, wherein the C-shaped portion of the inner surface further includes at least one protrusion extending away from the C-shaped portion of the inner surface, and wherein, upon coupling the syringe with the backstop, the at least one protrusion is configured to engage the flange and/or the barrel to create a space between the flange and/or the barrel and the C-shaped portion of the inner surface and to permit or promote airflow through the space between the C-shaped portion of the inner surface and the flange and/or the barrel, the backstop further having a cavity for receiving at least a portion of the flange, the cavity defined by opposing surfaces to limit axial movement of the backstop.

2. The injection device as in claim 1 , wherein the at least one protrusion includes at least two protrusions.

3. The injection device as in claim 2 , wherein the at least two protrusions includes at least three protrusions.

4. The injection device as in claim 3 , wherein the at least three protrusions includes at least four protrusions.

5. The injection device as in claim 4 , wherein the at least four protrusions includes at least five protrusions.

6. The injection device as in claim 5 , wherein the at least five protrusions includes at least seven protrusions.

7. The injection device as in claim 1 , wherein the inner surface of the backstop extends around at least a portion of the barrel of the syringe and the at least one protrusion engages the barrel of the syringe.

8. The injection device as in claim 1 , wherein the backstop includes a collar portion defining the inner surface generally extending around at least a portion of the barrel.

9. The injection device as in claim 8 , wherein the collar portion is configured to engage the syringe in a snap-fit relationship.

10. The injection device as in claim 1 , wherein the barrel defines an axis and the at least one protrusion is a rib extending generally parallel with the axis.

11. The injection device as in claim 1 , wherein the inner surface of the backstop includes the opposing surfaces defining the cavity and the at least one protrusion extends away from at least one of the opposing surfaces.

12. The injection device as in claim 11 , wherein the opposing surfaces include a top opposing surface and a bottom opposing surface, the at least one protrusion includes at least one protrusion on the top opposing surface and at least one protrusion on the bottom opposing surface.

13. The injection device as in claim 12 , wherein the at least one protrusion on the top opposing surface includes at least two ribs on the top opposing surface and the at least one protrusion on the bottom opposing surface includes at least two ribs on the bottom opposing surface.

14. The injection device as in claim 1 , wherein the syringe is a pre-filled syringe containing a medicament.

15. The injection device as in claim 14 , wherein the medicament comprises a VEGF antagonist.

16. The injection device as in claim 15 , wherein the VEGF antagonist comprises a non-antibody VEGF antagonist.

17. The injection device as in claim 15 , wherein the VEGF antagonist comprises a VEGF-Trap.

18. The injection device as in claim 17 , wherein the VEGF-Trap comprises an aflibercept.

19. A packaging assembly comprising:
a syringe having a barrel and a flange;
a backstop configured to be coupled with the syringe adjacent to the flange during use of the syringe for drug delivery; and
a packaging configured to receive an entire length of the syringe coupled with the backstop while physically supporting at least a portion of the syringe, wherein the packaging includes a cavity surface including a C-shaped portion and at least one protrusion disposed on the C-shaped portion of the cavity surface and extending away from the C-shaped portion of the cavity surface, and wherein the at least one protrusion is configured to engage the barrel of the syringe upon the syringe being disposed within the packaging to create a space between the syringe and at least a bottom portion of the C-shaped portion of the cavity surface and to permit or promote airflow through the space between at least the bottom portion of the C-shaped portion of the cavity surface and the syringe.

20. The packaging assembly as in claim 19 , wherein the at least one protrusion includes at least two protrusions.

21. The packaging assembly as in claim 20 , wherein the at least two protrusions are configured to engage the syringe in a snap-fit relationship.

22. A packaging assembly comprising:
a syringe having a barrel, a plunger rod at least partially received within the barrel, and a flange;
a backstop configured to be coupled with the syringe adjacent to the flange during use of the syringe for drug delivery; and
a packaging configured to receive an entire length of the syringe coupled with the backstop while physically supporting at least a portion of the syringe, wherein the packaging includes a cavity surface defining at least one raised wall section configured to engage the plunger rod of the syringe and resist and/or limit movement of the plunger rod, the cavity surface of the packaging further includes a C-shaped portion and at least one protrusion disposed on the C-shaped portion of the cavity surface and extending away from the C-shaped portion of the cavity surface, and wherein the at least one protrusion is configured to engage the barrel of the syringe upon the syringe being disposed within the packaging to create a space between the syringe and at least a bottom portion of the C-shaped portion of the cavity surface and to permit or promote airflow through the space between at least the bottom portion of the C-shaped portion of the cavity surface and the syringe.

23. An injection device comprising:
a syringe having a barrel and a flange; and
a backstop configured to be coupled with the syringe adjacent to the flange during use of the syringe for drug delivery such that axial movement of the backstop is limited by the backstop, the backstop having an inner surface including a C-shaped portion extending around at least a portion of a circumference of the syringe for an entire length of the C-shaped portion, wherein the C-shaped portion of the inner surface is interrupted by an opening that permits the backstop to receive the flange and/or the barrel, wherein the C-shaped portion of the inner surface further includes at least one protrusion extending away from the C-shaped portion of the inner surface, and wherein, upon coupling the syringe with the backstop, the at least one protrusion is configured to engage the flange and/or the barrel to create a space between the flange and/or the barrel and the C-shaped portion of the inner surface and to permit or promote airflow through the space between the C-shaped portion of the inner surface and the flange and/or the barrel such that only the at least one protrusion contacts the flange and/or the barrel of the syringe.

Assignees

• Amgen Inc

Inventors

• Mismar Wael
• Liu Jessica Hai
• Bourelle Dylan
• Wu Chia-Jung
• Devitt Shaun
• Schalhoub Kenneth G
• Desai Tej
• Due Mads Schjoth
• Bitong Anthony
• Keshishian Arin
• Balli-Cruz Chelsea
• Burquel Pierre
• Oba Ryan
• Guirguis Malak

Classifications

• A61M5/001 Primary

  Apparatus specially adapted for cleaning or sterilising syringes or needles · CPC title

• A61M2005/3139

  Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips · CPC title

• A61M5/31505

  Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit · CPC title

• A61M5/002

  Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics (needle protection, e.g. caps, A61M5/3202; for sharps A61B50/3001) · CPC title

• A61K39/395

  Antibodies (agglutinins A61K38/36 {; as drug carriers A61K47/50}); Immunoglobulins; Immune serum, e.g. antilymphocytic serum · CPC title