Medical device packaging and related methods

Patent metadata

Field	Value
Publication number	US-2023248898-A1
Application number	US-202318164171-A
Country	US
Kind code	A1
Filing date	Feb 3, 2023
Priority date	Feb 4, 2022
Publication date	Aug 10, 2023
Grant date	—

Abstract

A packaging comprising a tray having an opening, a cavity including at least three cavity portions, a plurality of sidewalls, and a base; and a sterile syringe contained within the cavity, wherein the sterile syringe is pre-filled with a medicament or other fluid; wherein a first cavity portion comprises a plunger rod of the sterile syringe, a second cavity portion comprises a barrel of the sterile syringe, and a third cavity portion comprises a needle attachment portion of the sterile syringe, wherein the at least three cavity portions are connected to one another by intermediate narrowed portions, and wherein each of the narrowed portions includes a first sidewall, a second sidewall, a base, and a plurality of geometric features projecting into the narrowed portions to position the sterile syringe away from the plurality of sidewalls.

First claim

What is claimed is:

1 . A packaging comprising:
a tray having an opening, a cavity including at least three cavity portions, a plurality of sidewalls, and a base; and a sterile syringe contained within the cavity, wherein the sterile syringe is pre-filled with a medicament or other fluid;
wherein a first cavity portion comprises a plunger rod of the sterile syringe, a second cavity portion comprises a barrel of the sterile syringe, and a third cavity portion comprises a needle attachment portion of the sterile syringe, wherein the three cavity portions are connected to one another by intermediate narrowed portions, and
wherein each of the narrowed portions includes a first sidewall, a second sidewall, a base, and a plurality of geometric features projecting into the narrowed portions to position the sterile syringe away from the plurality of sidewalls.

2 . The packaging of claim 1 , wherein the first sidewall of the narrowed portion includes a first geometric feature and the second sidewall of the narrowed portion includes a second geometric feature.

3 . The packaging of claim 2 , wherein a distance between the first geometric feature and the second geometric feature is less than about 2.0 mm than the width of the portion of the sterile syringe contained within the narrowed portions.

4 . The packaging of claim 2 , wherein a distance between the first geometric feature and the second geometric feature ranges from about 5.5 mm to about 6.5 mm.

5 . The packaging of claim 2 , wherein the base of the narrowed portion includes a third geometric feature.

6 . The packaging of claim 1 , further comprising a projection associated with the tray at a location in line with a portion of the sterile syringe.

7 . The packaging of claim 1 , wherein the first cavity includes a flange portion configured for holding a flange of the syringe.

8 . The packaging of claim 7 , wherein a recessed portion is located between the flange portion and the first cavity.

9 . The packaging of claim 1 , wherein each of the at least three cavity portions has a rectangular shape.

10 . The packaging of claim 1 , wherein each of the at least three cavity portions has a rectangular shape with a radius around each corner.

11 . A packaging for a sterile syringe, the packaging comprising:
a tray having an opening, a cavity including a plurality of cavity portions, a plurality of sidewalls, and a base;
wherein the plurality of cavity portions are connected to one another by intermediate narrowed portions, each narrowed portion including a first sidewall, a second sidewall, and a base,
wherein each of the first sidewall, the second sidewall, and the base, includes a geometric feature extending away from the corresponding sidewall or base and projecting into the narrowed portion to position the sterile syringe away from the plurality of sidewall;
a lip surrounding the opening, wherein the lip extends radially outward from the cavity and defines a periphery of the tray; and a removable cover having a periphery that is adhered to the lip, wherein the removable cover is permeable to a gaseous sterilant.

12 . The packaging of claim 11 , wherein the geometric feature on the first sidewall is a first geometric feature and the geometric feature on the second sidewall is a second geometric feature, and a distance between the first geometric feature and the second geometric feature ranges from about 5.5 mm to about 6.5 mm.

13 . The packaging of claim 11 , wherein the plurality of cavity portions includes at least three cavity portions, and wherein a first cavity portion comprises a plunger rod of the sterile syringe, a second cavity portion comprises a barrel of the sterile syringe, and a third cavity portion comprises a needle attachment portion of the sterile syringe.

14 . The packaging of claim 11 , wherein the gaseous sterilant is one or more of vaporized hydrogen peroxide, ethylene oxide, or nitrous oxide.

15 . A method of removing an externally-sterilized syringe from a packaging, the packaging including a tray having a cavity, a plurality of geometric features associated with the cavity, and a removable cover, the method comprising:
removing the removable cover so as to expose an opening of the tray; grasping a portion of the externally-sterilized syringe held by the plurality of geometric features; and ejecting the externally-sterilized syringe from the tray, wherein the ejecting step also causes the plurality of geometric features to move away from the externally-sterilized syringe to release the externally-sterilized syringe from the tray.

16 . The method of claim 15 , wherein the externally-sterilized syringe is pre-filled with aflibercept, ranibizumab, bevacizumab, conbercept, OPT-302, RTH258 (brolocizumab), a pegylated designed ankyrin repeating protein (DARPin), or RG7716.

17 . The method of claim 15 , wherein the tray is fabricated from a material including one or more of polypropylene, polystyrene, polyethylene, polycarbonate, polyvinyl chloride, or polyethylene terephthalate glycol.

18 . The method of claim 15 , wherein the removable cover is permeable to a gaseous sterilant.

19 . The method of claim 18 , wherein the gaseous sterilant is vaporized hydrogen peroxide.

20 . The method of claim 15 , further comprising pushing a portion of the packaging forwards the cavity of the tray, wherein pushing the portion of the packaging causes a portion of the tray to flex.

21 . The method of claim 20 , wherein pushing the portion of the tray causes the externally-sterilized syringe to release from the plurality of geometric features.

22 . The method of claim 20 , wherein the portion of the packaging that is pushed includes a deformable projection.

23 . The method of claim 15 , wherein the tray is fabricated from a thermoforming injection or blow molding technology.

Assignees

• Regeneron Pharma

Inventors

• Cook Andrew
• Bradford Victor
• Smith Jason
• Ulla Sibgat

Classifications

• A61L2103/15

  Laboratory, medical or dentistry appliances, e.g. catheters or sharps · CPC title

• A61M2209/06

  Packaging for specific medical equipment · CPC title

• A61M2207/00

  Methods of manufacture, assembly or production · CPC title

• A61L2202/182

  Rigid packaging means · CPC title

• A61L2101/02

  Inorganic materials · CPC title