Light absorption coefficient distribution estimation device, concentration measurement device, and method for controlling light absorption coefficient distribution estimation device
US-9380968-B2 · Jul 5, 2016 · US
US12007275B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12007275-B2 |
| Application number | US-202217576117-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 14, 2022 |
| Priority date | Apr 21, 2016 |
| Publication date | Jun 11, 2024 |
| Grant date | Jun 11, 2024 |
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Systems and methods for determining one or more properties of a sample are disclosed. The systems and methods disclosed can be capable of measuring along multiple locations and can reimage and resolve multiple optical paths within the sample. The system can be configured with one-layer or two-layers of optics suitable for a compact system. The optics can be simplified to reduce the number and complexity of the coated optical surfaces, et al. on effects, manufacturing tolerance stack-up problems, and interference-based spectroscopic errors. The size, number, and placement of the optics can enable multiple simultaneous or non-simultaneous measurements at various locations across and within the sample. Moreover, the systems can be configured with an optical spacer window located between the sample and the optics, and methods to account for changes in optical paths due to inclusion of the optical spacer window are disclosed.
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What is claimed is: 1. A system for determining properties of a sample, the system comprising: one or more light sources that emit light; a detector array comprising detector pixels; an illumination optic; a first optics unit, comprising: a first substrate; and a first plurality of collection optics on the first substrate; a second optics unit, comprising: a second substrate; and a second plurality of collection optics on the second substrate; and one or more multiplexers configured to combine the light received from the one or more light sources, wherein: the illumination optic receives the light and directs the light toward the sample; the first plurality of collection optics receive at least a portion of the light that is reflected from the sample; each optic of the first plurality of collection optics transmits a portion of the light to a respective one of the second plurality of collection optics; and each optic of the second plurality of collection optics transmits a portion of the light to a respective detector pixel of the detector array. 2. The system of claim 1 , wherein: the system comprises an outcoupler with a surface; the outcoupler transmits light to the illumination optic; the illumination optic is positioned on a first side of the second optics unit; and the outcoupler surface is in contact with a second side of the second optics unit, opposite the first side. 3. The system of claim 1 , wherein: the system comprises an outcoupler positioned to provide light to the illumination optic; the illumination optic is positioned on a first side of the second substrate; the detector pixels are facing a second side of the second substrate; and the second side is opposite the first side of the second substrate. 4. The system of claim 1 , further comprising an aperture layer located on the first substrate. 5. The system of claim 4 , wherein the aperture layer comprises metal. 6. The system of claim 4 , wherein: the second plurality of collection optics are positioned on a first side of the second substrate; and the aperture layer is located on the first side of the second substrate. 7. The system of claim 1 , wherein: the one or more multiplexers are disposed on a third substrate; and the detector array is positioned below the third substrate. 8. The system of claim 1 , wherein: the illumination optic is positioned on a first side of the second optics unit. 9. A system comprising: one or more light sources that emit light directed toward an exterior interface of the system; a first set of optics that receives at least a portion of the light; a second set of optics; and a detector array with multiple detector pixels, wherein the detector array, first set of optics and second set of optics are arranged to form: a first trio, comprising: a first optic of the first set of optics that collects at least a portion of the light that enters back into the system on a first optical path and changes a first angle of the light; a second optic of the second set of optics that receives the light on the first optical path from the first optic; and a first detector pixel of the detector array that receives the light on the first optical path from the second optic; a second trio, comprising: a third optic of the first set of optics that collects at least a portion of the light that enters back into the system on a second optical path and changes a second angle of the light; a fourth optic of the second set of optics that receives the light on the second optical path from the third optic; and a second detector pixel of the detector array that receives the light on the second optical path from the fourth optic, wherein the first trio and the second trio resolve different angles of incidence of light. 10. The system of claim 9 , wherein: the system further comprises: a first optics unit, comprising: a first substrate; and the first set optics; a second optics unit, comprising: a second substrate; and the second set of optics; the first set of optics are disposed on the first substrate; the second set of optics are disposed on a first side of the second substrate; and the detector array is facing a second side of the second substrate. 11. The system of claim 9 , wherein: the first trio is associated with a first angle of incidence of reflected light; the second trio is associated with a second angle of incidence of reflected light different than the first angle of incidence of reflected light. 12. The system of claim 9 , wherein: the system further comprises: a first optics unit, comprising: a first substrate; and the first set of optics; a second optics unit, comprising: a second substrate; and the second set of optics; the first set of optics is disposed on the first optics unit; and the one or more second optics are integrated in the second optics unit. 13. The system of claim 9 , wherein: the first trio is associated with a first angle of incidence and the first optical path having a first path length; and the second trio is associated with a second angle of incidence and the second optical path having a second path length different than the first path length. 14. A method for determining properties of a sample, comprising: emitting light using one or more light sources; combining the light emitted by the one or more light sources using one or more multiplexers; directing the light toward the sample using an illumination optic; receiving at least a portion of a return of the light at a first optics unit, the first optics unit, comprising: a first substrate; a first plurality of collection optics disposed on the first substrate; redirecting the light using the first plurality of collection optics and towards a second optics unit, the second optics unit, comprising: a second substrate; a second plurality of collection optics on the second substrate, wherein: each optic of the first plurality of collection optics transmits a portion of the light to a respective one of the second plurality of collection optics; and each optic of the second plurality of collection optics transmits a portion of the light to a respective detector pixel of a detector array comprising detector pixels; and detecting light using the detector array. 15. The method of claim 14 , wherein: a first optic of the first plurality of collection optics is associated with a second optic of the second plurality of collection optics and a first detector pixel of the detector array; a third optic of the first plurality of collection optics is associated with a fourth optic of the second plurality of collection optics and a second detector pixel of the detector array. 16. The method of claim 15 , wherein: the first optic of the first plurality of collection optics, the second optic of the second plurality of collection optics and the first detector pixel are associated with a first angle of incidence of returned light; and the third optic of the first plurality of collection optics, the fourth optic of the second plurality of collection optics and the second detector pixel of the detector array are associated with a second angle of incidence of reflected light different than the first angle of incidence of returned light. 17. The method of claim 14 , wherein: the one or more multiplexers are disposed on a third substrate; and the detector array is positioned below the third substrate. 18. The method of claim 14 , wherein: the illumination optic is positio
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