Designs and fabrication of nanogap sensors

Patent metadata

Field	Value
Publication number	US-11740226-B2
Application number	US-201816651832-A
Country	US
Kind code	B2
Filing date	Oct 8, 2018
Priority date	Oct 13, 2017
Publication date	Aug 29, 2023
Grant date	Aug 29, 2023

Abstract

Embodiments of the disclosure provide various nanogap sensor designs (e.g., horizontal nanogap sensors, vertical nanogap sensors, arrays of multiple nanogap sensors, various arrangements for making electrical connections to the electrodes of nanogap sensors, etc.), as well as various methods which may be used to fabricate at least some of the proposed sensors. The nanogap sensors proposed herein may operate as molecular sensors to help identify chemical species through electrical measurements using at least a pair of electrodes separated by a nanogap.

First claim

The invention claimed is:

1. A transducer device for analyzing one or more fluid analytes, the transducer device comprising:
a nanogap sensor over a substrate, the nanogap sensor including a first electrode having a planar shape and a second electrode, the second electrode opposite the first electrode and separated from the first electrode by a nanogap for receiving a liquid analyte, wherein each of the first electrode and the second electrode is parallel to the substrate;
a first interconnect configured to provide electrical connectivity to the first electrode; and
a second interconnect configured to provide electrical connectivity to the second electrode,
wherein:
at least a portion of the second electrode forms a planar, fully-released cantilever suspended directly over at least a majority of the first electrode,
the planar shape of the first electrode and the planar shape of the fully-released cantilever are parallel to one another and function as a parallel plate capacitor;
the first interconnect is in a first layer over the substrate,
the nanogap sensor is in a second layer over the substrate, and
the second interconnect is in a third layer over the substrate, the second layer being between the first layer and the third layer, and the first layer being between the substrate and the second layer.

2. The transducer device according to claim 1 , wherein at least a portion of the second electrode forms a structure resembling a projecting beam over at least a portion of the first electrode.

3. The transducer device according to claim 1 , further comprising a solid dielectric material between at least a portion of the second electrode and at least a portion of the first electrode.

4. The transducer device according to claim 1 , wherein a mean surface roughness of the first electrode is less than 10 nm.

5. The transducer device according to claim 1 , wherein the nanogap is oriented horizontally with respect to the substrate.

6. The transducer device according to claim 1 , wherein a distance between the first electrode and the second electrode is between 1 and 100 nm.

7. The transducer device according to claim 1 , further comprising a first layer disposed over at least a portion of the first electrode, the first layer including one or more thiols, dithiols, or alkanethiols.

8. The transducer device according to claim 1 , further comprising a second layer disposed over at least a portion of the second electrode, the second layer including one or more thiols, dithiols, or alkanethiols.

9. The transducer device according to claim 1 , further comprising one or more fluidic windows configured to support provision of the one or more fluid analytes to the nanogap.

10. A transducer device for analyzing one or more fluid analytes, the transducer device comprising:
a nanogap sensor over a substrate, the nanogap sensor including a first electrode having a planar shape and a second electrode, the second electrode opposite the first electrode and separated from the first electrode by a nanogap for receiving a liquid analyte, wherein each of the first electrode and the second electrode is parallel to the substrate;
a first interconnect configured to provide electrical connectivity to the first electrode; and
a second interconnect configured to provide electrical connectivity to the second electrode,
wherein:
both the first interconnect and the second interconnect are between the substrate and the nanogap sensor;
at least a portion of the second electrode forms a planar, fully-released cantilever directly suspended over at least a majority of the first electrode, and
the planar shape of the first electrode and the planar shape of the fully-released cantilever are parallel to one another and function as a parallel plate capacitor.

11. The transducer device according to claim 10 , wherein at least a portion of the second electrode forms a structure resembling a projecting beam over at least a portion of the first electrode.

12. The transducer device according to claim 10 , further comprising a solid dielectric material between at least a portion of the second electrode and at least a portion of the first electrode.

13. The transducer device according to claim 10 , wherein a mean surface roughness of the first electrode is less than 10 nm.

14. The transducer device according to claim 10 , wherein the nanogap is oriented horizontally with respect to the substrate.

15. The transducer device according to claim 10 , wherein a distance between the first electrode and the second electrode is between 1 and 100 nm.

16. The transducer device according to claim 10 , further comprising a first layer disposed over at least a portion of the first electrode, the first layer including one or more thiols, dithiols, or alkanethiols.

17. The transducer device according to claim 10 , further comprising a second layer disposed over at least a portion of the second electrode, the second layer including one or more thiols, dithiols, or alkanethiols.

18. The transducer device according to claim 10 , further comprising one or more fluidic windows configured to support provision of the one or more fluid analytes to the nanogap.

Assignees

• Analog Devices International Unlimited Co

Inventors

• Antoine Christophe
• Jain Himanshu
• Canty Matthew Thomas
• Mcloughlin Christina B
• Lucey Daniel Joseph
• Mcdermott Sinead Maire
• O'Brien Stephen
• Stenson Bernard
• Geary Shane
• Lane William Allan
• Coln Michael
• Alea Mark De Leon

Classifications

• B81B1/00

  Devices without movable or flexible elements, e.g. microcapillary devices · CPC title

• G01N33/48721 Primary

  Investigating individual macromolecules, e.g. by translocation through nanopores (Coulter counters in general G01N15/12; fabrication methods for nanoscale apertures B81B1/00; sequencing of nucleic acids C12Q1/68) · CPC title

• G01N27/3278

  involving nanosized elements, e.g. nanogaps or nanoparticles (nanopores G01N33/48721; magnetic beads G01N27/745) · CPC title

• G01N27/327

  Biochemical electrodes {, e.g. electrical or mechanical details for in vitro measurements} · CPC title

• G01N33/487

  of liquid biological material · CPC title