Automated fluid handling system

Patent metadata

Field	Value
Publication number	US-11650219-B2
Application number	US-202016788836-A
Country	US
Kind code	B2
Filing date	Feb 12, 2020
Priority date	Jun 9, 2009
Publication date	May 16, 2023
Grant date	May 16, 2023

Abstract

Automated fluid handling system comprising a housing and two or more fluid handling units arranged as interchangeable modular components with an external fluidics section and an internal non fluidics section, and wherein the housing comprises a liquid handling panel with two or more of component positions for receiving said interchangeable modular components such that the external fluidics section is separated from the non fluidics section by the liquid handling panel.

First claim

The invention claimed is:

1. A pH valve for an automated liquid chromatography system, the pH valve comprising:
an inlet port, and outlet port;
the pH valve being configured to include an integrated flow cell and a pH electrode for in-line monitoring of pH levels in the automated liquid chromatography system, wherein the pH valve is configured to direct flow to or to bypass the pH electrode.

2. The pH valve of claim 1 , wherein the liquid chromatography system comprises a master control unit arranged to automatically detect fluid handling units when inserted into fluid handling unit receiving positions.

3. The pH valve of claim 1 , wherein the pH valve comprises a dedicated CPU allowing the pH valve to perform operations in response to instructions over a system bus.

4. The pH valve of claim 1 , wherein the pH valve forms part of a fluid handling unit, the fluid handling unit corresponding in size and shape to a corresponding fluid handling unit receiving position of the automated liquid chromatography system, wherein said liquid chromatography system is adapted to allow each fluid handling unit to be freely and independently positioned in any one of the fluid handling unit receiving positions of a housing unit.

5. The pH valve of claim 4 , wherein an internal section of the at least one fluid handling unit comprises electronics, electrical components, or control means.

6. The pH valve of claim 4 , wherein the fluid handling unit comprises an enclosure with one or more air inlet openings.

7. The pH valve of claim 6 , wherein the one or more air inlet openings are on the section of the fluid handling unit that is inserted into the fluid handling unit receiving position of the housing unit.

Assignees

• Cytiva Sweden Ab

Inventors

• Blomberg Johan
• Lundkvist Mats

Classifications

• G01N2030/8804

  automated systems · CPC title

• Y10T137/6525

  Air heated or cooled [fan, fins, or channels] · CPC title

• B01D15/10

  characterised by constructional or operational features · CPC title

• B01D17/12

  Auxiliary equipment particularly adapted for use with liquid-separating apparatus, e.g. control circuits · CPC title

• G01N30/24

  Automatic injection systems · CPC title