Ion suppressor and ion chromatograph

Patent metadata

Field	Value
Publication number	US-11531010-B2
Application number	US-201716624436-A
Country	US
Kind code	B2
Filing date	Jul 24, 2017
Priority date	Jul 24, 2017
Publication date	Dec 20, 2022
Grant date	Dec 20, 2022

Abstract

An ion suppressor includes ion exchange membranes between a pair of electrodes. Regeneration liquid channels are provided in the spaces between the electrodes and the ion exchange membranes, and an eluent channel is provided between the ion exchange membranes. In the space between the electrode and the eluent channel, an element that increases the resistance in the voltage application direction is disposed. For example, ion permeable membranes are disposed in contact with the ion exchange membrane, thereby increasing the resistance in the voltage application direction.

First claim

The invention claimed is:

1. An ion suppressor that exchanges ions in an eluent from a separation column of an ion chromatograph, the ion suppressor comprising:
a first ion exchange membrane and a second ion exchange membrane are disposed between a pair of electrodes of a first electrode and a second electrode,
an eluent channel for allowing passage of the eluent from the separation column of the ion chromatograph is provided in a space between the first ion exchange membrane and the second ion exchange membrane,
a first regeneration liquid channel for allowing passage of a regeneration liquid that regenerates the first ion exchange membrane is provided in a space between the first electrode and the first ion exchange membrane,
a second regeneration liquid channel for allowing passage of a regeneration liquid that regenerates the second ion exchange membrane is provided in a space between the second electrode and the second ion exchange membrane, and
a resistance increase element that increases a resistance in a voltage application direction is disposed between the first regeneration liquid channel and the eluent channel and/or between the second regeneration liquid channel and the eluent channel;
wherein
an ion permeable membrane is disposed as the resistance increase element, and
the ion permeable membrane is higher in resistivity than the first ion exchange membrane and/or the second ion exchange membrane.

2. The ion suppressor according to claim 1 , wherein the ion permeable membrane is in contact with at least one of the first ion exchange membrane and the second ion exchange membrane, and
the ion permeable membrane allows permeation of ions that permeate the first ion exchange membrane and the second ion exchange membrane.

3. The ion suppressor according to claim 2 , wherein the ion permeable membrane is higher in resistivity than the ion exchange membrane disposed in contact with the ion permeable membrane.

4. The ion suppressor according to claim 2 , wherein the ion permeable membrane is lower in swelling ratio with respect to water than the ion exchange membrane disposed in contact with the ion permeable membrane.

5. The ion suppressor according to claim 2 , wherein the ion permeable membrane is smaller in area than the ion exchange membrane disposed in contact with the ion permeable membrane.

6. The ion suppressor according to claim 2 , wherein the ion permeable membrane is disposed in contact with the eluent channel.

7. The ion suppressor according to claim 2 , wherein the ion permeable membrane is disposed in contact with the first regeneration liquid channel or the second regeneration liquid channel.

8. The ion suppressor according to claim 2 , wherein the first ion exchange membrane and the second ion exchange membrane are cation exchange membranes.

9. The ion suppressor according to claim 8 , wherein the cation exchange membrane comprises a fluorine-based material.

10. The ion suppressor according to claim 9 , wherein the ion permeable membrane is a hydrocarbon-based ion exchange membrane.

11. The ion suppressor according to claim 2 , wherein the resistance increase element is disposed in at least one of a region of the first regeneration liquid channel facing the eluent channel and a region of the second regeneration liquid channel facing the eluent channel.

12. The ion suppressor according to claim 11 , wherein the regeneration liquid channel with the resistance increase element disposed is lower in charge density on a side close to the eluent channel than on a side close to the electrode.

13. The ion suppressor according to claim 12 , wherein two or more laminated mesh materials that differ in charge quantity are disposed in the regeneration liquid channel with the resistance increase element disposed, and
a mesh material disposed on a side close to the eluent channel is lower in charge density than a mesh material disposed on a side close to the electrode.

14. A chromatograph comprising:
a separation column that separates an ion to be measured;
an electric conductivity meter that measures an electric conductivity of an eluent from the separation column; and
the ion suppressor according to claim 1 in a channel between the separation column and the electric conductivity meter.

15. An ion suppressor that exchanges ions in an eluent from a separation column of an ion chromatograph, the ion suppressor comprising:
a first ion exchange membrane and a second ion exchange membrane are disposed between a pair of electrodes of a first electrode and a second electrode,
an eluent channel for allowing passage of the eluent from the separation column of the ion chromatograph is provided in a space between the first ion exchange membrane and the second ion exchange membrane,
a first regeneration liquid channel for allowing passage of a regeneration liquid that regenerates the first ion exchange membrane is provided in a space between the first electrode and the first ion exchange membrane,
a second regeneration liquid channel for allowing passage of a regeneration liquid that regenerates the second ion exchange membrane is provided in a space between the second electrode and the second ion exchange membrane, and
a resistance increase element that increases a resistance in a voltage application direction is disposed between the first regeneration liquid channel and the eluent channel and/or between the second regeneration liquid channel and the eluent channel,
wherein
an ion permeable membrane is disposed as the resistance increase element, and
the ion permeable membrane is lower in swelling ratio with respect to water than the first ion exchange membrane and/or the second ion exchange membrane.

16. An ion suppressor that exchanges ions in an eluent from a separation column of an ion chromatograph, the ion suppressor comprising:
a first ion exchange membrane and a second ion exchange membrane are disposed between a pair of electrodes of a first electrode and a second electrode,
an eluent channel for allowing passage of the eluent from the separation column of the ion chromatograph is provided in a space between the first ion exchange membrane and the second ion exchange membrane,
a first regeneration liquid channel for allowing passage of a regeneration liquid that regenerates the first ion exchange membrane is provided in a space between the first electrode and the first ion exchange membrane,
a second regeneration liquid channel for allowing passage of a regeneration liquid that regenerates the second ion exchange membrane is provided in a space between the second electrode and the second ion exchange membrane, and
a resistance increase element that increases a resistance in a voltage application direction is disposed between the first regeneration liquid channel and the eluent channel and/or between the second regeneration liquid channel and the eluent channel,
wherein
an ion permeable membrane is disposed as the resistance increase element, and
the regeneration liquid channel with the resistance increase element disposed is lower in charge density on a side close to the eluent channel than on a side close to the electrode.

Assignees

• Shimadzu Corp

Inventors

• Sakamoto Katsumasa
• Fujiwara Masanori

Classifications

• B01D15/361

  Ion-exchange · CPC title

• B01D15/24 Primary

  relating to the treatment of the fractions to be distributed · CPC title

• B01D15/08

  Selective adsorption, e.g. chromatography · CPC title

• B01D65/02

  Membrane cleaning or sterilisation {; Membrane regeneration} · CPC title

• G01N2030/645

  electrical conductivity detectors · CPC title