Glycosyl hesperetin and process for producing the same and uses thereof

Patent metadata

Field	Value
Publication number	US-11453694-B2
Application number	US-202016878911-A
Country	US
Kind code	B2
Filing date	May 20, 2020
Priority date	Mar 3, 2014
Publication date	Sep 27, 2022
Grant date	Sep 27, 2022

Abstract

The present invention aims to provide a novel glycosyl hesperetin, which is significantly reduced in miscellaneous tastes characteristic of conventional products containing glycosyl hesperetin, and a method for producing the same and uses thereof; and the objects are solved by providing a glycosyl hesperetin which comprises glycosyl hesperetin in an amount of 90% or more by mass but less than 100% by mass, on a dry solid basis, but it does not substantially contain furfural, and a method for producing the same and uses thereof.

First claim

The invention claimed is:

1. A glycosyl hesperetin composition, which comprises as glycosyl hesperetin α-glycosyl hesperidin and either or both of hesperidin and 7-O-β-glucosyl hesperetin in an amount of 90% by mass or more but less than 100% by mass, on a dry solid basis, wherein the content of furfural measured on GC/MS analysis is less than 200 ppb, on a dry solid basis.

2. The glycosyl hesperetin composition of claim 1 , wherein the content of 4-methoxystylene measured on GC/MS analysis is less than 30 ppb, on a dry solid basis.

3. The glycosyl hesperetin composition of claim 1 , wherein the content of α-glycosyl hesperidin is 50% by mass or more but less than 100% by mass, on a dry solid basis.

4. The glycosyl hesperetin composition of claim 1 , wherein said α-glycosyl hesperidin is α-glucosyl hesperidin.

5. The glycosyl hesperetin composition of claim 4 , wherein the content of α-glucosyl hesperidin is 60% by mass or more but 90% by mass or lower, on a dry solid basis.

6. A method for reducing the miscellaneous tastes of a glycosyl hesperetin composition comprising as glycosyl hesperetin α-glycosyl hesperidin and either or both of hesperidin and 7-O-β-glucosyl hesperetin in an amount of 90% or more by mass but less than 100% by mass, on a dry solid basis, said method comprising a step of contacting said glycosyl hesperetin composition with an inorganic reducing agent to reduce the miscellaneous tastes.

7. The method of claim 6 , wherein the content of α-glycosyl hesperidin is 50% by mass or more but less than 100% by mass to said glycosyl hesperetin, on a dry solid basis.

8. The method of claim 6 , wherein said α-glycosyl hesperidin is α-glucosyl hesperidin.

9. The method of claim 6 , wherein said inorganic reducing agent is a sulfite.

Assignees

• Hayashibara Co

Inventors

• KAMBE Mitsuyuki
• Nishi Koichi
• Kawashima Akira
• Yasuda Akiko
• Mitsuzumi Hitoshi
• Ariyasu Toshio

Classifications

• A61K8/602

  Glycosides, e.g. rutin · CPC title

• A61P31/12

  Antivirals · CPC title

• A23L33/15

  Vitamins · CPC title

• A23L27/84

  Flavour masking or reducing agents · CPC title

• A23L2/52

  Adding ingredients (adding preservatives A23B70/10) · CPC title