On site generated performic acid compositions for teat treatment

Patent metadata

Field	Value
Publication number	US-11260040-B2
Application number	US-201916442096-A
Country	US
Kind code	B2
Filing date	Jun 14, 2019
Priority date	Jun 15, 2018
Publication date	Mar 1, 2022
Grant date	Mar 1, 2022

Abstract

The present disclosure relates generally to peroxyformic acid forming compositions and methods for forming peroxyformic acid, preferably in situ, and peroxyformic acid formed by said compositions and methods for the purpose of treating an animal tissue and providing an antimicrobial function thereon. present disclosure in particular relates to a residue-free teat treatment composition for the treatment of an animal tissue, especially bovine teats, which provides antimicrobial efficacy and does not leave a non-food ingredient residue on treated teats.

First claim

The claimed invention is:

1. An antimicrobial teat dip composition comprising:
hydrogen peroxide or a hydrogen peroxide forming compound;
an ester of an alcohol and formic acid;
a dye, wherein the dye is red #40, yellow #5, yellow #6, or a mixture thereof; and
water;
wherein the pH of the composition is between about 2 and about 7; and
wherein the dye results in the coloring of a teat without interfering with the antimicrobial function of the composition.

2. The composition of claim 1 , wherein the ester of an alcohol and formic acid comprises a glycerol formate, an ethylene glycol formate, a pentaerythritol formate, a mannitol formate, a propylene glycol formate, a sorbitol formate, a sugar formate, a methyl formate, an ethyl formate, a propyl formate, a butyl formate, a heptyl formate, a pentyl formate, a benzyl formate, or a mixture thereof.

3. The composition of claim 2 , wherein the sugar formate is a glycerol formate, a sucrose formate, a dextrin formate, a maltodextrin formate, a starch formate, or a mixture thereof.

4. The composition of claim 1 , wherein the dye is yellow #6.

5. The composition of claim 1 , further comprising an emollient, a foaming surfactant, a buffering agent, a stabilizing agent, or a combination thereof.

6. The composition of claim 5 , wherein the emollient comprises glycerin, glycerol, propylene glycol, dipropylene glycol, sorbitol, aloe, shea butter, coco butter, allantoin, or a mixture thereof; wherein the stabilizing agent comprises a phosphonate, a dicarboxylic acid, a pyridine carboxylic acid, or a mixture thereof; wherein the buffering agent comprises succinic acid or a salt thereof; and wherein the foaming surfactant is polysorbate and/or dioctyl sulfosuccinate sodium salt.

7. The composition of claim 1 , wherein the composition is a concentrated composition comprising between about 50 wt. % and about 99 wt. % water, and between about 0.1 wt. % and about 20 wt. % of hydrogen peroxide or a hydrogen peroxide forming compound.

8. The composition of claim 1 , wherein the composition is a ready-to-use composition with between about 90.0 wt. % and about 99.9 wt. % water, between about 50 ppm and about 2 wt. % of hydrogen peroxide or a hydrogen peroxide forming compound, between about 50 ppm and about 350 ppm of performic acid; and wherein the composition is stable for at least 24 hours.

9. The composition of claim 8 , wherein the composition provides a 4-log reduction in Staphylococcus aureus and Escherichia coli.

10. An antimicrobial performic acid forming teat dip composition comprising:
a first premix and a second premix; wherein the first premix comprises an ester of an alcohol and formic acid; wherein the second premix comprises hydrogen peroxide or a hydrogen peroxide forming compound and a dye, wherein the dye is red #40, yellow #5, yellow #6, or a mixture thereof;
wherein the first premix and second premix, when combined provide a performic acid composition having a pH between about 2.5 and about 7;
wherein the performic acid composition provides a 4-log reduction in Staphylococcus aureus and Escherichia coli ; and
wherein the dye results in the coloring of a teat without interfering with the antimicrobial function of the composition.

11. The composition of claim 10 , wherein the ester of an alcohol and formic acid comprises a glycerol formate, a pentaerythritol formate, a mannitol formate, a propylene glycol formate, a sorbitol formate, a sugar formate, a methyl formate, an ethyl formate, a propyl formate, a butyl formate, a heptyl formate, a pentyl formate, a benzyl formate, or a mixture thereof.

12. The composition of claim 11 , further comprising an emollient, a foaming surfactant, a buffering agent, a stabilizing agent, or a combination thereof.

13. The composition of claim 12 , wherein the stabilizing agent comprises a phosphonate, a dicarboxylic acid, a pyridine carboxylic acid, or a mixture thereof;
wherein the emollient comprises glycerin, glycerol, propylene glycol, dipropylene glycol, sorbitol, aloe, shea butter, coco butter, allantoin, or a mixture thereof; wherein the buffering agent comprises succinic acid and/or a salt thereof; and wherein the foaming surfactant is polysorbate and/or dioctyl sulfosuccinate sodium salt.

14. The composition of claim 13 , further comprising a dye, wherein the dye is yellow #6.

15. The composition of claim 10 , wherein the second premix comprises between about 0.1 wt. % and about 20 wt. % of hydrogen peroxide or a hydrogen peroxide forming compound and between about 20 wt. % and about 65 wt. % water.

16. The composition of claim 15 , wherein the second premix further comprises between about 25 wt. % and about 75 wt. % humectant, a wetting agent in an amount between about 0.1 wt. % and about 7 wt. %, a stabilizing agent in an amount between about 0.001 wt. % and about 10 wt. %.

17. The composition of claim 10 , wherein the performic acid composition is a ready-to-use composition with between about 90.0 wt. % and about 99.9 wt. % water; wherein the composition has a performic acid concentration between about 50 ppm and about 350 ppm;
wherein the hydrogen peroxide or hydrogen peroxide forming compound is in a concentration between about 50 ppm and about 2 wt. %; and wherein the composition is stable for at least 24 hours.

18. A method of using the composition of claim 1 comprising:
applying the performic acid composition to an animal tissue; and
removing the performic acid composition from the animal tissue after at least 1 minute of contact.

19. The method of claim 18 , wherein the composition provides a 4-log reduction in Staphylococcus aureus and Escherichia coli.

Assignees

• Ecolab Usa Inc

Inventors

• Li Junzhong
• Thomas Alexander
• Prideaux Allison
• Mcsherry David D
• Morelli Joseph
• Staub Richard

Classifications

• A61P15/14

  for lactation disorders, e.g. galactorrhoea · CPC title

• A61K49/0071

  solution, solute · CPC title

• A61K47/24

  containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids · CPC title

• A61K47/22

  Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones · CPC title

• A61K47/12

  Carboxylic acids; Salts or anhydrides thereof · CPC title