Oral care composition

Patent metadata

Field	Value
Publication number	US-11253444-B2
Application number	US-201616309402-A
Country	US
Kind code	B2
Filing date	Jun 24, 2016
Priority date	Jun 24, 2016
Publication date	Feb 22, 2022
Grant date	Feb 22, 2022

Abstract

The present invention relates to an oral care composition for use in the treatment or prevention of erosive tooth demineralization, plaque, and caries. This oral care composition includes zinc lactate dihydrate, a stannous ion source, at least one phosphate salt, and a buffer system.

First claim

What is claimed is:

1. A method of treating or reducing demineralization of teeth in the oral cavity comprising administering an oral care composition to the oral cavity of a subject in need thereof, where the oral care composition, comprises an orally acceptable carrier and:
zinc lactate, wherein the composition comprises zinc lactate in an amount of about 2.5% by weight of the composition;
a stannous ion source, wherein the stannous ion source is stannous fluoride present in an amount of from 0.1 to 3% by weight of the oral care composition;
a phosphate salt, wherein the phosphate salt is selected from tetrasodium pyrophosphate and/or sodium tripolyphosphate, wherein the amount of the phosphate salt is from 1% to 10% by weight of the oral care composition;
a citrate buffer system, wherein the citrate buffer system comprises citric acid and trisodium citrate; and
about 4% propylene glycol.

2. The method of claim 1 , wherein the zinc lactate is zinc lactate dihydrate.

3. The method of claim 1 , wherein the orally acceptable carrier comprises water from 10 to 40% by weight of the oral care composition.

4. The method of claim 1 , which is a single phase composition.

5. The method according to claim 1 , wherein the oral care composition comprises:
a) about 2.5% zinc lactate;
b) about 3.6% citrate buffer;
c) about 0.45% stannous fluoride;
d) about 3% sodium tripolyphosphate (STPP); and
e) about 2% tetrasodium pyrophosphate (TSPP).

6. The method of claim 1 , wherein the oral care composition is a toothpaste or dental gel.

Assignees

• Colgate Palmolive Co

Inventors

• Dogu Nihal
• Vemishetti Kavita

Classifications

• A61K8/27

  Zinc; Compounds thereof · CPC title

• A61K8/365

  Hydroxycarboxylic acids; Ketocarboxylic acids · CPC title

• A61K8/345

  containing more than one hydroxy group · CPC title

• A61K8/362

  Polycarboxylic acids · CPC title

• A61K8/24

  Phosphorous; Compounds thereof · CPC title