Oral compositions containing polymethylsilsesquioxane particles

Patent metadata

Field	Value
Publication number	US-9566226-B2
Application number	US-201414249663-A
Country	US
Kind code	B2
Filing date	Apr 10, 2014
Priority date	Apr 10, 2013
Publication date	Feb 14, 2017
Grant date	Feb 14, 2017

Abstract

Oral compositions containing a polyorganosilsesquioxane particle, preferably polymethylsilsesquioxane particles, a stannous ion source, and an orally-acceptable carrier. Method of using such compositions for the cleaning and polishing of dental enamel, such methods including the step of applying such oral care compositions to the teeth of a user.

First claim

We claim:

1. An oral care composition having good cleaning and stability, said composition comprising:
a. at least 0.01%, by weight of the composition, of an abrasive comprising one or more polymethylsilsesquioxane particles wherein the polymethylsilsequioxane particles are spherical and smooth;
b. at least 0.01%, by weight of the composition, of an oral care active wherein the active comprises at least one stannous ion source; and
c. from 0.001% to about 99%, by weight of the composition, of an orally acceptable carrier;
wherein the oral care composition has a Pellicle Cleaning Ratio of greater than about 80 and wherein the oral care composition has a Radioactive Dentine Abrasion of less than about 250; and
wherein the polymethylsilsesquioxane particles are substantially insoluble in the composition.

2. The composition of claim 1 wherein the polymethylsilsesquioxane particles have an average volume weighted mean particle size of from about 1 to about 20 microns.

3. The composition of claim 1 wherein the stannous ion is stannous fluoride.

4. The composition of claim 1 wherein the stannous ion is a stannous salt selected from the group consisting of stannous fluoride, stannous chloride, stannous gluconate, stannous acetate, stannous tartrate, stannous oxalate, stannous sulfate, stannous citrate, stannous malonate, stannous lactate, stannous phosphate, stannous pyrophosphate, stannous bromide, stannous iodide, and combinations thereof.

5. The composition of claim 1 wherein the composition comprises from about 50 ppm to about 15,000 ppm of the stannous ion.

6. The composition of claim 1 wherein the composition comprises from about 0.5 to about 40%, by weight of the composition, of the polymethylsilsesquioxane particles.

7. The composition of claim 1 wherein the orally acceptable carrier is selected from buffering agents, secondary abrasive materials, alkali metal bicarbonate salts, thickening agents, gel networks, humectants, water, surfactants, titanium dioxide, flavor agents, coolants, sweetening agents, coloring agents, other suitable materials, and mixtures thereof.

8. The composition of claim 1 wherein the orally acceptable carrier comprises a secondary abrasive selected from calcium pyrophosphate, precipitated silica, fused silica, and mixtures thereof.

9. The composition of claim 1 , wherein the abrasive comprises from about 50% to about 100%, by weight of all the abrasive in the composition, of the polymethylsilsesquioxane particles.

10. The composition of claim 1 wherein the stannous ions have a compatibility of greater than 80% after two weeks of storage at 25° C.

11. The composition of claim 1 wherein the composition is a dentifrice and is in a form selected from pastes, slurries, gels or combinations thereof.

12. The composition of claim 1 wherein the oral care active further comprises a chelant selected from polymeric organophosphate compounds including ethoxylated and non-ethoxylated mono or di alkyl phosphates or phosphonates.

13. The composition of claim 1 wherein the oral care active further comprises one or more essential oils.

14. The composition of claim 13 comprising two essential oils wherein the first essential oil is selected from the group consisting of acyclic or non-ring structures and a second essential oil is selected from ring-containing structures.

15. The composition of claim 1 wherein the orally acceptable carrier comprises a gel network.

16. The composition of claim 1 wherein the orally acceptable carrier comprises a polymeric thickener.

17. An oral care composition comprising a polymethylsilsesquioxane particle abrasive, a stannous ion source, a gel network, and a chelant; wherein the polymethylsilsequioxane particles are spherical and smooth.

18. The composition according to claim 1 further comprising a zinc ion source and a chelant.

19. A method of reducing plaque, gingivitis, sensitivity, oral malodor, erosion, cavities, calculus, inflammation, and staining by administering to a subject's oral cavity the composition of claim 1 .

Assignees

• Procter & Gamble

Inventors

• Midha Sanjeev
• Leblanc Michael Jude
• Schneiderman Eva
• Hughes Iain Allan

Classifications

• A61K8/20

  Halogens; Compounds thereof · CPC title

• A61Q11/00

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title

• A61K2800/412

  Microsized, i.e. having sizes between 0.1 and 100 microns · CPC title

• A61K8/0241

  Containing particulates characterized by their shape and/or structure (see also A61K8/04, A61K8/11, and A61K8/14, further aspects are classified in A61K2800/40 and subcodes) · CPC title

• A61K8/025

  Explicitly spheroidal or spherical shape · CPC title