Surface modified nanoparticles

Patent metadata

Field	Value
Publication number	US-11053436-B2
Application number	US-202016870146-A
Country	US
Kind code	B2
Filing date	May 8, 2020
Priority date	Dec 22, 2011
Publication date	Jul 6, 2021
Grant date	Jul 6, 2021

Abstract

Surface-modified nanoparticles are produced by associating ligand interactive agents with the surface of a nanoparticle. The ligand interactive agents are bound to surface modifying ligands that are tailored to impart particular solubility and/or compatibility properties. The ligand interactive agents are crosslinked via a linking/crosslinking agent. The linking/crosslinking agent may provide a binding site for binding the surface modifying ligands to the ligand interactive agents.

First claim

What is claimed is:

1. A surface-modified nanoparticle comprising:
a ligand interactive agent-nanoparticle association complex;
a linking/crosslinking agent bound to a ligand interactive agent of the ligand interactive agent-nanoparticle association complex; and
a surface modifying ligand bound to the linking/crosslinking agent, the surface modifying ligand is a monomethoxy polyethylene oxide, a monohydroxy polydimethylsiloxane, trimethylolpropane triglycidyl ether, a polyether, or guaifenesin.

2. The surface-modified nanoparticle of claim 1 , wherein a nanoparticle of the ligand interactive agent-nanoparticle association complex comprises a metal oxide.

3. The surface-modified nanoparticle of claim 2 , wherein the metal oxide is selected from the group consisting of an iron oxide, titanium oxide, zinc oxide, zirconium oxide, and aluminum oxide.

4. The surface-modified nanoparticle of claim 1 , wherein a nanoparticle of the ligand interactive agent-nanoparticle association complex comprises a metal.

5. The surface-modified nanoparticle of claim 4 , wherein the metal is gold or silver.

6. The surface-modified nanoparticle of claim 1 , wherein a nanoparticle of the ligand interactive agent-nanoparticle association complex comprises a semiconductor material.

7. The surface-modified nanoparticle of claim 6 , wherein the semiconductor material is selected from the group consisting of CdS, CdSe, CdTe, ZnS, ZnSe, ZnTe, InP, InAs, InSb, AlP, A 1 S, AlAs, AlSb, GaN, GaP, GaAs, GaSb, PbS, PbSe, Si, Ge, and any combination thereof.

8. The surface-modified nanoparticle of claim 1 , wherein a nanoparticle of the ligand interactive agent-nanoparticle association complex is a core/shell nanoparticle.

9. The surface-modified nanoparticle of claim 8 , wherein the core/shell nanoparticle has two or more shells.

10. The surface-modified nanoparticle of claim 1 , wherein the linking/crosslinking agent is a melamine-based compound.

11. The surface-modified nanoparticle of claim 1 , wherein the ligand interactive agent comprises any one of a thiol moiety, an amine moiety, a carboxylic acid moiety and a phosphine moiety.

12. The surface-modified nanoparticle of claim 1 , wherein the ligand interactive agent is a C 8 -C 20 fatty acid.

13. The surface-modified nanoparticle of claim 1 , wherein the ligand interactive agent is a C 8 -C 20 fatty acid ester.

14. A surface-modified nanoparticle comprising:
a ligand interactive agent-nanoparticle association complex;
a melamine-based compound bound to a ligand interactive agent of the ligand interactive agent-nanoparticle association complex; and
a surface modifying ligand bound to the melamine-based compound.

15. The surface-modified nanoparticle of claim 14 , wherein the surface modifying ligand is a monomethoxy polyethylene oxide, a monohydroxy polydimethylsiloxane, trimethylolpropane triglycidyl ether, a polyether, or guaifenesin.

16. The surface-modified nanoparticle of claim 14 , wherein a nanoparticle of the ligand interactive agent-nanoparticle association complex comprises a metal, a metal oxide, or a semiconductor material.

17. The surface-modified nanoparticle of claim 14 , wherein the ligand interactive agent comprises any one of a thiol moiety, an amine moiety, a carboxylic acid moiety and a phosphine moiety.

18. The surface-modified nanoparticle of claim 14 , wherein the ligand interactive agent is a C 8 -C 20 fatty acid or a C 8 -C 20 fatty acid ester.

19. The surface-modified nanoparticle of claim 14 , wherein the surface modifying ligand is configured to render the surface-modified nanoparticle compatible with a host material.

20. A surface-modified nanoparticle comprising:
a ligand interactive agent-nanoparticle association complex comprising a nanoparticle, the nanoparticle comprising gold or silver;
a linking/crosslinking agent bound to a ligand interactive agent of the ligand interactive agent-nanoparticle association complex; and
a surface modifying ligand bound to the linking/crosslinking agent.

Assignees

• Nanoco Technologies Ltd

Inventors

• Naasani Imad

Classifications

• H10H20/8515

  not being in contact with the bodies · CPC title

• H10H20/8512

  Wavelength conversion materials · CPC title

• B82Y30/00

  Nanotechnology for materials or surface science, e.g. nanocomposites · CPC title

• C09K11/025

  non-luminescent particle coatings or suspension media · CPC title

• Y10S977/774

  Exhibiting three-dimensional carrier confinement, e.g. quantum dots · CPC title