Palladium-mediated ketolization
US-2018155361-A1 · Jun 7, 2018 · US
US10954249B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10954249-B2 |
| Application number | US-201816500924-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 3, 2018 |
| Priority date | Apr 5, 2017 |
| Publication date | Mar 23, 2021 |
| Grant date | Mar 23, 2021 |
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The present invention provides novel Compound (1) having tumor vascular remodeling effect and/or anti-CAF (Cancer Associated Fibroblasts) activity, or a pharmaceutically acceptable salt thereof, optionally in a pharmaceutically acceptable and medical uses thereof.
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What is claimed is: 1. A compound selected from the group consisting of: and salts thereof. 2. The compound of claim 1 , wherein the compound is of Formula (D-5), or a salt thereof. 3. The compound of claim 1 , wherein the compound is of Formula (D-4), or a salt thereof.
against CD28 or CD152 · CPC title
against proteinaceous materials, e.g. enzymes, hormones, lymphokines · CPC title
Antineoplastic agents · CPC title
in which the condensed system contains four or more hetero rings · CPC title
having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel · CPC title
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