Intermediates and methods for the synthesis of halichondrin b analogs
US-2015225415-A1 · Aug 13, 2015 · US
Intermediates for the preparation of analogs of Halichondrin B
US9303050B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9303050-B2 |
| Application number | US-201514624171-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 17, 2015 |
| Priority date | Jun 3, 2004 |
| Publication date | Apr 5, 2016 |
| Grant date | Apr 5, 2016 |
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Abstract
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Intermediates and methods of their use in the synthesis of analogs of halichondrin B are provided.
First claim
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The invention claimed is: 1. A compound of formula F-2d: wherein: R′ is —CH═CH 2 or —C(O)H; Alk is a C 1-4 straight or branched aliphatic group; and PG 5 is a suitable hydroxyl protecting group. 2. The compound of claim 1 , wherein PG 5 , taken with the oxygen atom to which it is bound, is an ester, silyl ether, alky…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
- C07D307/28Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US9303050B2 cover?
- Intermediates and methods of their use in the synthesis of analogs of halichondrin B are provided.
- Who is the assignee on this patent?
- Eisai R&D Man Co Ltd
- What technology area does this patent fall under?
- Primary CPC classification C07D307/28. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 7 related publications on this page (citations in our corpus or others sharing the same primary CPC).