Tannin-based antiproliferative pharmaceutical
US-2024293492-A1 · Sep 5, 2024 · US
US10426808B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10426808-B2 |
| Application number | US-201514802545-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 17, 2015 |
| Priority date | Jun 27, 2012 |
| Publication date | Oct 1, 2019 |
| Grant date | Oct 1, 2019 |
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Natural plant parts and extracts of plants selected from the group consisting of Quercus infectoria, Rhus chinensis and Terminalia chebula containing compounds such as gallic acid, derivative of gallic acid, gallotannins and hydrolysable tannins have been found to control coccidiosis in poultry and, more specifically, coccidiosis caused by Eimeria spp. The plant parts and natural extracts result in a reduction of lesion score, oocysts per gram of fecal matter and mortality.
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We claim: 1. A method of controlling coccidiosis in animals, comprising the step of administering a plant extract to the animal, said plant extract from a plant selected from the group consisting of Quercus infectoria and Rhus chinensis, said plant extract being administered to the animals in a dose of from about 0.1 to 50 ppm. 2. The method of claim 1 , wherein the plant extract is administered to the animals in a dose of from about 2 to 20 ppm. 3. The method of claim 2 , wherein the plant extract is administered to the animals in a dose of from about 3 to 10 ppm. 4. The method of claim 1 , wherein the coccidiosis is caused by Eimeria spp. 5. The method of claim 4 , wherein the Eimeria spp. are selected from the group consisting of E. tenella, E. maxima and E. acervulina. 6. The method of claim 1 , wherein controlling coccidiosis includes a reduction in lesion score, oocysts per gram of fecal matter or mortality. 7. A method of reducing the activity of sporozoites in an animal infected with Eimeria spp., comprising the step of administering a plant extract to the animal, said plant extract from a plant selected from the group consisting of Quercus infectoria and Rhus chinensis, said plant extract being administered to the animals in a dose of from about 0.1 to 50 pp. 8. The method of claim 7 , wherein the plant extract is administered in a dose of from about 2 to 20 ppm. 9. The method of claim 8 , wherein the plant extract is administered in a dose of from about 3 to 10 ppm. 10. The method of claim 7 , wherein the coccidiosis is caused by Eimeria spp. 11. The method of claim 10 , wherein the Eimeria spp. are selected from the group consisting of E. tenella, E. maxima and E. acervulina. 12. The method of claim 7 , wherein controlling coccidiosis includes a reduction in lesion score, oocysts per gram of fecal matter or mortality. 13. A method of controlling coccidiosis in animals, comprising the step of administering a plant extract to the animal, said plant extract from Rhus chinensis , said plant extract being administered to the animals in a dose of from about 0.1 to 50 ppm.
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