Mixing device

Patent metadata

Field	Value
Publication number	US-10258947-B2
Application number	US-201715809195-A
Country	US
Kind code	B2
Filing date	Nov 10, 2017
Priority date	Nov 11, 2016
Publication date	Apr 16, 2019
Grant date	Apr 16, 2019

Abstract

Provided is a mixing device that is configured to install therein a multi-well plate including a plurality of wells capable of containing matter to be mixed and includes mixing mechanisms each of which mixes the matter to be mixed with a motor and is provided for each of the wells. The mixing mechanisms each includes a first rotator that is connected to the motor and rotates due to activation of the motor, a mixing rod that mixes the matter to be mixed, a second rotator that supports the mixing rod, a magnetic coupling mechanism that magnetically couples the first rotator to the second rotator, and a seal ring that surrounds an opening of the well and is capable of closing the well together with the second rotator.

First claim

What is claimed is:

1. A mixing device that is configured to install therein a multi-well plate including a plurality of wells capable of containing matter to be mixed and comprises mixing mechanisms each of which mixes the matter to be mixed with a motor and is provided for each of the wells, the mixing mechanisms each including
a first rotator that is connected to the motor and rotates due to activation of the motor,
a mixing rod that mixes the matter to be mixed,
a second rotator that supports the mixing rod,
a magnetic coupling mechanism that magnetically couples the first rotator to the second rotator, and
a seal ring that surrounds an opening of the well and is capable of closing the well together with the second rotator.

2. The mixing device according to claim 1 , wherein
the second rotator includes
a rotational portion that is coupled to the mixing rod, and
a bearing provided between the rotational portion and the seal ring.

3. The mixing device according to claim 2 , wherein
the rotational portion includes a rotational shaft that is coupled to the mixing rod,
the bearing includes
an inner race including a through-hole into which the mixing rod and the rotational shaft are inserted,
an outer race, and
a ball provided between the inner race and the outer race, and

the seal ring has an inner diameter equal to or smaller than an outer diameter of the inner race as the seal ring and the inner race are projected onto a plane orthogonal to the rotational shaft.

4. The mixing device according to claim 2 , wherein
the bearing is formed of at least one of a PEEK resin, a fluorocarbon polymer, and a polyphenylene sulfide.

5. The mixing device according to claim 1 , wherein
the second rotator includes a rotational portion that is coupled to the mixing rod, the mixing device further comprising
a ring member provided between the rotational portion and the seal ring.

6. The mixing device according to claim 1 , further comprising
a casing including a main surface portion that is opposed to an upper surface of the multi-well plate, wherein
the mixing mechanism is provided in the main surface portion.

7. The mixing device according to claim 6 , wherein
the casing has a stacked structure of
a motor-housing casing that houses the motor and the first rotator for each of the wells, and
a housing that retains the mixing rod, the second rotator, and the seal ring for each of the wells.

8. The mixing device according to claim 7 , wherein
the housing includes
a first flat surface that is adjacent to the motor-housing casing, and
a second flat surface that is opposed to the first flat surface, and

the second flat surface includes housing compartments each having a bottom, being provided for each of the wells, and housing the second rotator.

9. The mixing device according to claim 8 , further comprising
a mounting table on which the multi-well plate is placed.

10. The mixing device according to claim 7 , wherein
the housing is formed of at least one of a PEEK resin, a fluorocarbon polymer, and a polyphenylene sulfide.

11. The mixing device according to claim 1 , wherein
the magnetic coupling mechanism includes
a first magnet provided in the first rotator, and
a second magnet provided in the second rotator.

12. The mixing device according to claim 11 , wherein
the first rotator includes a first surface and a second surface that are disposed to be opposed to each other in a rotational-axis direction of the first rotator,
the first magnet includes two different magnetic poles and is provided in parallel to the rotational-axis direction such that one of the magnetic poles is located on a side of the first surface and the other is located on a side of the second surface, and
the magnetic poles of the first magnets, which are located on the side of the first surface, are all the same in the mixing mechanisms each provided for each of the wells.

13. The mixing device according to claim 1 , wherein
the motor is provided for each of the wells.

14. The mixing device according to claim 1 , wherein
the seal ring is formed of a fluorocarbon polymer or a fluorocarbon rubber.

15. The mixing device according to claim 1 , wherein
the mixing rod is formed of at least one of a PEEK resin, a fluorocarbon polymer, and a polyphenylene sulfide.

Assignees

• Ulvac Inc

Inventors

• Ozeki Tomomitsu

Classifications

• B01F13/1022 Primary

  Operations & Transport · mapped topic

• B01F7/1665

  Operations & Transport · mapped topic

• B01F15/00389

  Operations & Transport · mapped topic

• B01F13/0845

  Operations & Transport · mapped topic

• C12M23/12

  Well or multiwell plates (C12M25/04 takes precedence) · CPC title