Polymer substrates formed from carboxy functional acrylamide

Patent metadata

Field	Value
Publication number	US-10189956-B2
Application number	US-201815871863-A
Country	US
Kind code	B2
Filing date	Jan 15, 2018
Priority date	Jul 2, 2015
Publication date	Jan 29, 2019
Grant date	Jan 29, 2019

Abstract

A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.

First claim

What is claimed is:

1. A compound of the formula:

wherein R 1 is an alkyl group having between 3 and 10 carbons or is a polyether group having between 1 and 10 ether units, wherein R 2 is a linear or branched alkyl group having between 3 and 8 carbons or a silyl group, and wherein R 3 is hydrogen or an alkyl group having between 1 and 6 carbons.

2. The compound of claim 1 , wherein R 1 is an alkyl group having between 3 and 6 carbons.

3. The compound of claim 2 , wherein R 1 is an alkyl group having between 3 and 5 carbons.

4. The compound of claim 1 , wherein R 1 is a polyether group having 2 to 6 units.

5. The compound of claim 1 , wherein the units of R 1 include ethylene oxide or propylene oxide units.

6. The compound of claim 1 , wherein R 2 is a branched alkyl group.

7. The compound of claim 6 , wherein R 2 is a branched alkyl group having between 3 and 5 carbons.

8. The compound of claim 7 , wherein R 2 is a branched alkyl group having 4 carbons.

9. The compound of claim 1 , wherein R 3 is hydrogen.

10. The compound of claim 1 , wherein R 3 is a methyl or ethyl group.

11. A population of particles having a coefficient of variance of not greater than 5% and comprising a polymer derived from polymerization of a compound of the formula:

wherein R 1 is an alkyl group having between 3 and 10 carbons or is a polyether group having between 1 and 10 ether units, wherein R 2 is a linear or branched alkyl group having between 3 and 8 carbons or a silyl group, and wherein R 3 is hydrogen or an alkyl group having between 1 and 6 carbons; and
wherein after removal of R 2 , the particle absorbs at least 300 wt % and not greater than 10 6 wt % water based on the weight of the polymer when exposed to water.

12. The population of particles of claim 11 , wherein the polymer is further derived from the polymerization of protected acrylamide or protected hydroxyalkyl acrylamide with the compound.

13. The population of particles of claim 11 , wherein the polymer is further derived from the polymerization of a crosslinker with the compound.

14. The population of particles of claim 13 , wherein the crosslinker comprises a diacrylamide.

15. The population of particles of claim 14 , wherein the diacrylamide includes N,N′-(ethane-1,2-diyl)bis(2-hydroxylethyl)acrylamide, N,N′-(2-hydroxypropane-1,3-diyl)diacrylamide, a protected derivative thereof, or a combination thereof.

16. The population of particles of claim 11 , wherein R 1 is an alkyl group having between 3 and 6 carbons.

17. The population of particles of claim 16 , wherein R 1 is an alkyl group having between 3 and 5 carbons.

18. The population of particles of claim 11 , wherein R 1 is a polyether group having 2 to 6 units.

19. The population of particles of claim 11 , wherein the units of R 1 include ethylene oxide or propylene oxide units.

20. The population of particles of claim 11 , wherein R 2 is a branched alkyl group.

Assignees

• Life Tech As
• Life Technologies Corp

Inventors

• Fonnum Geir
• Menchen Steven M
• Gokmen M Talha
• Lundberg Pontus
• Thwar Prasanna Krishnan
• Lui Alfred
• Lu Lily
• Hinz Wolfgang
• Husaboe Lene
• Breivold Elisabeth
• Molteberg Astrid Evenroed
• Larsen Synne

Classifications

• C08F230/08

  containing silicon · CPC title

• C08F8/12

  Hydrolysis · CPC title

• C08J3/075 Primary

  Macromolecular gels · CPC title

• C08J2333/26

  Homopolymers or copolymers of acrylamide or methacrylamide · CPC title

• C08F220/70

  Nitriles; Amides; Imides · CPC title