Compounds and uses thereof for the modulation of hemoglobin
US-2016031865-A1 · Feb 4, 2016 · US
US9981939B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9981939-B2 |
| Application number | US-201414776603-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 10, 2014 |
| Priority date | Mar 15, 2013 |
| Publication date | May 29, 2018 |
| Grant date | May 29, 2018 |
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Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.
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What is claimed is: 1. A compound selected from: or a pharmaceutically acceptable salt thereof. 2. The compound of claim 1 , wherein the compound is: or a pharmaceutically acceptable salt thereof. 3. The compound of claim 1 , wherein the compound is: or a pharmaceutically acceptable salt thereof. 4. The compound of claim 1 , wherein the compound is: or a pharmaceutically acceptable salt thereof. 5. The compound of claim 1 , wherein the compound is: or a pharmaceutically acceptable salt thereof. 6. The compound of claim 1 , wherein the compound is: or a pharmaceutically acceptable salt thereof. 7. A pharmaceutical composition comprising a compound of claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.
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