Traditional chinese medicine composition for sober-up and hepatic protection and a process for preparing the same

Patent metadata

Field	Value
Publication number	US-9968644-B2
Application number	US-201615091954-A
Country	US
Kind code	B2
Filing date	Apr 6, 2016
Priority date	Apr 27, 2015
Publication date	May 15, 2018
Grant date	May 15, 2018

Abstract

The present invention relates to traditional Chinese medicine, particularly to a traditional Chinese medicine composition for sober-up and hepatic protection and a process for preparing the same. This composition is made from Radix Puerariae, Semen Hoveniae and Fructus Gardeniae. This composition has no significant effect on the body weight of mice. The hepatic TG level in animals of 1.400 g/kg·bw dosage group is significantly lower than that of the model control group, while the hepatic GSH level is significantly higher than that of the model control group. The degree of hepatic steatosis in animals of 1.400 g/kg·bw dosage group is significantly lower than that of the model control group. Therefore, the composition of the present invention has auxiliary protective effects on liver damages caused by alcohol. The process for preparing the composition comprises: extracting Radix Puerariae, Semen Hoveniae and Fructus Gardeniae with water, concentrating, drying, and pulverizing the extract.

First claim

The invention claimed is:

1. A method for preparing a traditional Chinese medicine composition, which is made from raw materials in the following parts by mass: 6 to 12 parts of Radix Puerariae, 3 to 6 parts of Semen Hoveniae, and 1 to 3 parts of Fructus Gardeniae,
wherein the method comprises: extracting Radix Puerariae, Semen Hoveniae and Fructus Gardeniae with water, concentrating, drying, and pulverizing the extract, to obtain the traditional Chinese medicine composition.

2. The preparation method according to claim 1 , wherein the mass of water is 8 to 12 times the sum of the mass of Radix Puerariae, Semen Hoveniae and Fructus Gardeniae.

3. The preparation method according to claim 1 , wherein the extraction is carried out by decoction, and the decoction is conducted twice, each for 2 hours.

4. The preparation method according to claim 1 , wherein the concentration is conducted to achieve a relative density of 1.0 to 1.5.

5. The method according to claim 1 , wherein the traditional Chinese medicine composition is made from raw materials in the following parts by mass: 8 to 10 parts of Radix Puerariae, 4 to 5 parts of Semen Hoveniae, and 1.5 to 2.5 parts of Fructus Gardeniae.

6. The method according to claim 1 , wherein the traditional Chinese medicine composition is made from raw materials in the following parts by mass: 9 parts of Radix Puerariae, 4.5 parts of Semen Hoveniae, and 2 parts of Fructus Gardeniae.

Assignees

• Infinitus China Co Ltd

Inventors

• Yu Qingtao
• Ge Yazhong
• Ma Chung Wah
• LEE Wai Sum

Classifications

• A61P39/02

  Antidotes · CPC title

• A61K9/5031

  obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide) · CPC title

• A61P1/16

  for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics · CPC title

• A61K36/488

  Pueraria (kudzu) · CPC title

• A61K36/72

  Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree · CPC title