3D printer

Patent metadata

Field	Value
Publication number	US-9968437-B2
Application number	US-201514746631-A
Country	US
Kind code	B2
Filing date	Jun 22, 2015
Priority date	Jun 22, 2015
Publication date	May 15, 2018
Grant date	May 15, 2018

Abstract

A method of reproducing a biological object includes 3D-imaging the object and generating a mold using a 3D printer; obtaining cells from a donor site on the object; preparing a live cell suspension using the cells from the donor site; forming a scaffold in the mold with collagen and seeding the scaffold with live cells, growing the cells in the mold and curing the collagen; and surgically implanting the object into a living subject, where the cells continue to live in the living subject.

First claim

What is claimed is:

1. A method of forming a biological object, comprising:
obtaining cells from a donor site;
preparing live cells from the donor site and storing the live cells in a mobile handheld dispenser with embedded camera and computer vision in communication with a mobile computer over a wireless network, wherein the embedded camera captures view of the biological object;
forming a 3D scaffold and seeding the 3D scaffold with live cells from the mobile dispenser with embedded camera and computer vision;
further dispensing more cells on the 3D scaffold according to one or more predetermined dimensions of the object, wherein the mobile dispenser is controlled by gesture detected by computer vision; and
growing the cells in the 3D scaffold, where the cells continue to live in the living subject.

2. The method of claim 1 , comprising grafting a three-dimensional irregularly-shaped object.

3. The method of claim 1 , wherein the seeded cells comprise harvested skin cells.

4. The method of claim 1 , comprising forming the scaffold with a photocrosslinkable interpenetrating polymeric network (IPN) of collagen and hyaluronic acid (HA).

5. The method of claim 1 , comprising printing a body fragment.

6. The method of claim 1 , comprising printing materials with selected from the group consisting of collagen, hyaluronic acid, and tissues.

7. The method of claim 1 , comprising printing a selected part, a skin, a nose or ear portion.

8. The method of claim 1 , comprising transmitting a target area image to a remote medical professional for modification prior to printing.

9. The method of claim 1 , comprising:
imaging a target area with a camera and creating an imaged target area;
recognizing the imaged target area by image processing.

10. The method of claim 1 , comprising using a camera controlled by a processor to determine if a bio-material nozzle is within dispensing range of the imaged target area.

11. The method of claim 1 , comprising injecting materials onto a target area based on an imaged target area.

12. The method of claim 1 , comprising depositing materials over predetermined regions to form a predefined part, skin, nose or ear.

13. The method of claim 1 , comprising capturing gestures made with the printer and dispensing cells accordingly.

14. The method of claim 1 , comprising providing a heat source or a light source that heats or illuminates a biological surface near a deposit nozzle.

15. A method of forming a biological object, comprising:
obtaining cells from a donor site for the object;
preparing a live cell suspension using the cells from the donor site;
forming a 3D scaffold on a mold to be implanted in a living subject and seeding the scaffold with live cells using an untethered handheld pen with embedded camera and wherein the pen operation is controlled by computer vision in accordance with user gestures captured by the embedded camera and according to one or more predetermined dimensions of the object based on computer vision, wherein the gestures provide identifying information about the object, where the cells continue to live in the living subject.

16. The method of claim 15 , comprising depositing material only over predetermined regions to form a body structure, a skin area, a nose or an ear.

17. A method of forming a biological object, comprising:
obtaining cells from a donor site for the object;
preparing a live cell suspension using the cells from the donor site;
forming a 3D scaffold and seeding the scaffold with live cells using an untethered handheld device with embedded camera and computer vision; and
capturing device motion with a spatial component and a time component made with the untethered handheld device and controlling the handheld device according to the gestures; where the cells continue to live in the living subject.

18. The method of claim 17 , comprising grafting a three-dimensional irregularly-shaped object.

19. The method of claim 17 , wherein the seeded cells comprise harvested skin cells.

20. The method of claim 17 , comprising forming the scaffold with a photocrosslinkable interpenetrating polymeric network (IPN) of collagen and hyaluronic acid (HA).

Assignees

• Tran Bao

Inventors

• Tran Bao

Classifications

• A61F2240/004

  Using a positive or negative model, e.g. moulds · CPC title

• A61F2240/002

  Designing or making customized prostheses · CPC title

• A61L27/24

  Collagen · CPC title

• A61L2300/414

  Growth factors · CPC title

• B33Y80/00

  Products made by additive manufacturing · CPC title