Eye mounted device for therapeutic agent release
US-12167978-B2 · Dec 17, 2024 · US
US9931507B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9931507-B2 |
| Application number | US-201615207425-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 11, 2016 |
| Priority date | Apr 28, 2005 |
| Publication date | Apr 3, 2018 |
| Grant date | Apr 3, 2018 |
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The present invention is an improved hermetic package for a retinal prosthesis implanted in the human body. The retinal prosthesis includes a flexible circuit electrode array suitable to stimulate the retina while connected to a hermetic package on the outside of the eye, the hermetic package including a cover and a base where the cover is bonded to the base such that the cover and base form the hermetic package.
Opening claim text (preview).
What we claim is: 1. A retinal prosthesis comprising: a biocompatible package comprising a planar base, including an electrically non-conductive substrate and biocompatible patterned metallization comprising gold on the non-conductive substrate, a circuit attached directly to a first side of the base wherein the circuit is smaller than the base, and a rounded cover, the base and the rounded cover forming the biocompatible package; a molded polymer body pre-curved to match the curvature of a typical sclera and including suture tabs in the molded polymer body suitable to attach the biocompatible package to an outside surface of a sclera; and a flexible circuit electrically connected to the circuit, the flexible circuit extending from the biocompatible package and suitable to pass through a pars plana and having an array of electrodes suitable to stimulate retinal tissue. 2. The retinal prosthesis according to claim 1 , wherein the molded body is curved to approximate the shape of the sclera. 3. The retinal prosthesis according to claim 1 , further comprising a coil receiving electrical power to power the circuit. 4. The retinal prosthesis according to claim 1 , wherein the electrically non-conductive substrate contains ceramic. 5. The retinal prosthesis according to claim 1 , wherein the patterned metallization is multiple layer metallization and the circuit is bonded to the patterned metallization. 6. The retinal prosthesis according to claim 5 , wherein the multiple layer metallization is chosen to withstand braze temperatures. 7. The retinal prosthesis according to claim 6 , wherein the multiple layer metallization comprises more than one of the metals titanium, tantalum, gold, palladium, platinum or layers or alloys thereof. 8. The retinal prosthesis according to claim 1 , wherein the circuit is a flip-chip integrated circuit. 9. The retinal prosthesis according to claim 1 , wherein the circuit is a wire bonded circuit. 10. The retinal prosthesis according to claim 1 , wherein the cover includes a wall and a lid and the wall is brazed to the base. 11. The retinal prosthesis according to claim 1 , wherein the flexible circuit is bump bonded to the base with conductive bumps. 12. The retinal prosthesis according to claim 8 , further comprising a polymer underfill under the flip-chip integrated circuit. 13. The retinal prosthesis according to claim 11 , wherein the conductive bumps contain at least one conductive polymer. 14. The retinal prosthesis according to claim 11 , wherein the conductive bumps contain at least one conductive epoxy or polyimide. 15. The retinal prosthesis according to claim 1 , further comprising a getter. 16. The retinal prosthesis according to claim 15 , wherein the getter is placed on the inside of the cover.
between a chip and a stacked insulating package substrate, interposer or RDL · CPC title
between a chip and a stacked insulating package substrate, interposer or RDL · CPC title
Bump connectors and die-attach connectors · CPC title
Anchoring of the implants, e.g. fixation · CPC title
Constructional arrangements, e.g. casings · CPC title
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