Treatment of obesity using non-daily administration of 6-O-(4-dimethylaminoethoxy) cinnamoyl fumagillol
US-9173865-B2 · Nov 3, 2015 · US
US9925166B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9925166-B2 |
| Application number | US-201615093953-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 8, 2016 |
| Priority date | Jul 18, 2008 |
| Publication date | Mar 27, 2018 |
| Grant date | Mar 27, 2018 |
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The invention herein generally relates to pharmaceutical formulations and methods of treating an overweight or obese subject, and overweight- or obesity-related conditions.
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What is claimed is: 1. A method of treating an overweight or obese subject in need thereof, the method comprising: orally administering to the subject a pharmaceutical composition comprising about 0.001 mg/kg to about 1 mg/kg of body weight per day of a compound selected from the group consisting of fumagillin, fumagillol, and salts thereof, and a pharmaceutically acceptable excipient. 2. The method according to claim 1 , wherein the subject is a human. 3. A method of treating an overweight or obese subject in need thereof comprising orally treating the subject with about 0.001 mg/kg to about 1 mg/kg of body weight per day of a compound selected from the group consisting of fumagillin, fumagillol and salts thereof.
Anorexiants; Antiobesity agents · CPC title
Mouth and digestive tract, i.e. intraoral and peroral administration · CPC title
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca · CPC title
having three-membered rings, e.g. oxirane, fumagillin · CPC title
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