Trans-2-decenoic acid derivative and drug containing same
US-9428477-B2 · Aug 30, 2016 · US
US9925163B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9925163-B2 |
| Application number | US-201515316110-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 5, 2015 |
| Priority date | Jun 6, 2014 |
| Publication date | Mar 27, 2018 |
| Grant date | Mar 27, 2018 |
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The present invention relates generally to methods for the treatment and/or prophylaxis of neurological diseases and disorders involving administration of trans 10-HDA. In particular, the methods of the present invention are useful in the treatment and/or prophylaxis of acquired or progressive neurodevelopmental disorders and conditions in mammals. More particularly, methods are taught herein for the treatment and/or prophylaxis of diseases and disorders such as autism spectrum disorders.
Opening claim text (preview).
The invention claimed is: 1. A method for the treatment of autism spectrum disorder comprising administering to a mammal in need thereof an effective amount of trans 10-hydroxy-2-decenoic acid or a pharmaceutically acceptable salt thereof. 2. The method according to claim 1 wherein the autism spectrum disorder is selected from the group consisting of Autistic Disorder, Asperger's Disorder, Childhood Disintegrative Disorder and Pervasive Developmental Disorder-Not Otherwise Specified, and Rett syndrome. 3. The method according to claim 1 wherein the trans 10-hydroxy-2-decenoic acid or a pharmaceutically acceptable salt thereof is administered as a pharmaceutical composition. 4. The method according to claim 2 wherein the trans 10-hydroxy-2-decenoic acid or a pharmaceutically acceptable salt thereof is administered as a pharmaceutical composition. 5. The method according to claim 1 wherein the mammal is a human.
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