Trans-2-decenoic acid derivative and drug containing same

US9428477B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9428477-B2
Application numberUS-201314395241-A
CountryUS
Kind codeB2
Filing dateApr 26, 2013
Priority dateApr 27, 2012
Publication dateAug 30, 2016
Grant dateAug 30, 2016

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  1. Title

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  2. Abstract

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  4. Key dates

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  5. First independent claim

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention relates to a novel trans-2-decenoic acid derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical agent containing the compound as an active ingredient. The trans-2-decenoic acid derivative or a pharmaceutically acceptable salt, which is the compound of the present invention, is specifically represented by the general formula (I): wherein X is a substituent such as a 1-pyrrolidyl, a 3-thiazolizyl, or a piperidino, and the compound is highly useful as a pharmaceutical agent, such as a prophylactic or therapeutic agent for a peripheral nerve disorder induced by administration of an anticancer agent, a prophylactic or therapeutic agent for neurodegenerative diseases or mental diseases such as dementia, Alzheimer's disease, Parkinson's disease, diabetic neuropathy, depression, glaucoma, or autistic disorder spectrum, a therapeutic or repairing agent for spinal cord injury, analgesics against various pain diseases, or the like.

First claim

Opening claim text (preview).

The invention claimed is: 1. A trans-2-decenoic acid derivative represented by the following general formula (I′) or a pharmaceutically acceptable salt thereof: wherein X′ is: (a) a 1-pyrrolidyl substituted with carboxyl or alkoxycarbonyl, (b) a 3-thiazolidyl, (c) a piperidino substituted with oxo, hydroxy, alkoxy, carboxyl, alkoxycarbonyl, alkylam…

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What does patent US9428477B2 cover?
The present invention relates to a novel trans-2-decenoic acid derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical agent containing the compound as an active ingredient. The trans-2-decenoic acid derivative or a pharmaceutically acceptable salt, which is the compound of the present invention, is specifically represented by the general formula (I): …
Who is the assignee on this patent?
Nippon Zoki Pharmaceutical Co, Nagoya Ind Science Res Inst
What technology area does this patent fall under?
Primary CPC classification C07D295/185. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 30 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 4 related publications on this page (citations in our corpus or others sharing the same primary CPC).